Browsing by Keywords "Biomaterials"
Now showing items 1-14 of 14
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Applications of biomaterials in cancer diagnosis and treatment
(Bilkent University, 2013)Cancer remains to be a major burden of disease worldwide, despite the significant increase in the number of studies that focus on the development of novel diagnostic and treatment strategies. Recently, important part of ... -
Atomic force microscopy for the investigation of molecular and cellular behavior
(Elsevier, 2016-10)The present review details the methods used for the measurement of cells and their exudates using atomic force microscopy (AFM) and outlines the general conclusions drawn by the mechanical characterization of biological ... -
Atomic force microscopy: Methods and applications
(Elsevier, 2017)This chapter provides an overview of atomic force microscopy, covering the fundamental aspects of the associated instrumentation and methodology as well as representative results from the literature highlighting a variety ... -
Bioinspired materials for regenerative medicine and drug delivery applications
(Bilkent University, 2016-11)The structural organization and functional capabilities of natural materials have inspired many technological and scientific developments. Biological systems are under constant pressure for innovation due to the constraints ... -
Design and application of peptide nanofibers for modulating angiogenesis
(Bilkent University, 2016-06)Angiogenesis is important in many diseases, such as diabetic wound healing, cancer and corneal neovascularization. Angiogenesis can be induced or inhibited by complex biological systems. Mimicking the complexity in natural ... -
Design, synthesis and characterization of bioinspired nanomaterials for engineering and biomedicine
(Bilkent University, 2014)Nature is an inspirational school for materials scientists. Natural selection process puts a massive pressure on biological organisms giving rise to effective strategies for fabricating materials, which generally outperform ... -
Development and characterization of peptide nanofibers for cartilage regeneration
(Bilkent University, 2015-09)Articular cartilage is a tissue that is continuously exposed to cyclical compressive stresses, but exhibits no capacity for self-healing following trauma. Cartilage has a dense extracellular matrix that is sparsely ... -
Force and time-dependent self-assembly, disruption and recovery of supramolecular peptide amphiphile nanofibers
(Institute of Physics Publishing, 2018)Biological feedback mechanisms exert precise control over the initiation and termination of molecular self-assembly in response to environmental stimuli, while minimizing the formation and propagation of defects through ... -
Functional bacterial amyloid nanomaterials
(Bilkent University, 2016-11)Mis-folded or unfolded proteins tend to aggregate and aggregated structures are called as amyloids. Amyloid formation contributes to some human diseases and resulting in death in some cases. On the other hand, functional ... -
Investigation of the effects of bioactive peptide nanofibers on acute muscle injury regeneration
(Bilkent University, 2016-11)Skeletal muscle constitutes a large part of the human body. It is a hierarchically organized heterogeneous tissue and is composed of muscle fiber bundles, muscle fibers, myofibrils and myofilaments. Since muscle cells are ... -
Materials for articular cartilage regeneration
(Bentham Science Publishers B.V., 2012)Many health problems remaining to be untreatable throughout the human history can be overcome by utilizing new biomedical materials. Healing cartilage defects is one of the problems causing significant health issue due to ... -
Protein-releasing conductive anodized alumina membranes for nerve-interface materials
(Elsevier Ltd, 2016)Nanoporous anodized alumina membranes (AAMs) have numerous biomedical applications spanning from biosensors to controlled drug delivery and implant coatings. Although the use of AAM as an alternative bone implant surface ... -
Self-assembled peptide based biomaterials for drug delivery and regenerative medicine
(Bilkent University, 2016-06)Self-assembly is a nature inspired novel engineering tool to build functional new generation of adaptable and complex biomaterials with variety of chemical and physical properties based on recent discoveries at the ... -
Tuning viscoelastic properties of supermolecular peptide gels via dynamic covalent crosslinking
(Royal Society of Chemistry, 2015-12-19)A dynamic covalent crosslinking approach is used to crosslink supramolecular peptide gels. This novel approach facilitates tuning viscoelastic properties of the gel and enhances mechanical stability (storage modulus exceeding ...
