Browsing by Keywords "Biomarkers"
Now showing items 1-10 of 10
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Differential expression of colon cancer associated transcript1 (CCAT1) along the colonic adenoma-carcinoma sequence
(BioMed Central, 2013)Background: The transition from normal epithelium to adenoma and, to invasive carcinoma in the human colon is associated with acquired molecular events taking 5-10 years for malignant transformation. We discovered CCAT1, ... -
Discovery of cancer-specific and independent prognostic gene subsets of the slit-robo family using TCGA-PANCAN datasets
(Mary Ann Liebert, 2021-12-08)The Slit-Robo family of axon guidance molecules works in concert, playing important roles in organ devel opment and cancer. Expressions of individual Slit-Robo genes have been used in calculating univariable hazard ratios ... -
Dominant B-cell epitopes from cancer / stem cell antigen SOC2 recognized by serum samples from cancer patients
(AJCEI, 2014-08-30)Human sex determining region Y-box 2 (SOX2) is an important transcriptional factor involved in the pluripotency and stemness of human embryonic stem cells. SOX2 plays important roles in maintaining cancer stem cell ... -
A hybrid method for 6-DOF tracking of MRI-compatible robotic interventional devices
(2006-05)This paper reports a novel hybrid method of tracking the position and orientation of robotic medical instruments within the imaging volume of a magnetic resonance imaging (MRI) system. The method utilizes two complementary ... -
Identification of RNA-based biomarkers associated with manic episodes and lithium response in bipolar disorder
(Bilkent University, 2022-12)Bipolar disorder (BD) is one of the major mood disorders. A person afflicted with this neuropsychiatric disease undergoes episodes of depression and mania. BD ranks as the highest amongst all the mood disorders for having ... -
Identification of theranostic gene markers in cancers and prognostic validation in colorect al cancer
(Bilkent University, 2015-01)Colorectal cancer (CRC) is the fourth most prevalent cancer type worldwide. Although the 5-year survival rate of CRC is higher than many cancer types, prediction of prognosis and identification of accurate biomarkers still ... -
Impaired toll like receptor-7 and 9 induced immune activation in chronic spinal cord injured patients contributes to immune dysfunction
(Public Library of Science, 2017)Reduced immune activation or immunosuppression is seen in patients withneurological diseases. Urinary and respiratory infections mainly manifested as septicemia and pneumonia are the most frequent complications following ... -
Iterative H-minima-based marker-controlled watershed for cell nucleus segmentation
(John Wiley & Sons, Inc., 2016)Automated microscopy imaging systems facilitate high-throughput screening in molecular cellular biology research. The first step of these systems is cell nucleus segmentation, which has a great impact on the success of the ... -
Recent advances in microneedle-based sensors for sampling, diagnosis and monitoring of chronic diseases
(MDPI AG, 2021-08-25)Chronic diseases (CDs) are noncommunicable illnesses with long-term symptoms accounting for ~70% of all deaths worldwide. For the diagnosis and prognosis of CDs, accurate biomarker detection is essential. Currently, the ... -
Renin angiotensin system genes are biomarkers for personalized treatment of acute myeloid leukemia with Doxorubicin as well as etoposide
(Public Library of Science, 2020)Despite the availability of various treatment protocols, response to therapy in patients with Acute Myeloid Leukemia (AML) remains largely unpredictable. Transcriptomic profiling studies have thus far revealed the presence ...
