Now showing items 1-19 of 19

    • Amphiphilic peptide coated superparamagnetic iron oxide nanoparticles for in vivo MR tumor imaging 

      Ozdemir, A.; Ekiz, M. S.; Dilli, A.; Guler, M. O.; Tekinay, A. B. (Royal Society of Chemistry, 2016)
      Magnetic resonance imaging (MRI) is a noninvasive imaging technique that provides high spatial resolution and depth with pronounced soft-tissue contrast for in vivo imaging. A broad variety of strategies have been employed ...
    • Bioactive peptide functionalized aligned cyclodextrin nanofibers for neurite outgrowth 

      Hamsici, S.; Cinar, G.; Celebioglu A.; Uyar T.; Tekinay, A. B.; Guler, M. O. (Royal Society of Chemistry, 2017)
      Guidance of neurite extension and establishment of neural connectivity hold great importance for neural tissue regeneration and neural conduit implants. Although bioactive-epitope functionalized synthetic or natural polymeric ...
    • Biocompatibility studies on lanthanum oxide nanoparticles 

      Brabu, B.; Haribabu, S.; Revathy, M.; Anitha, S.; Thangapandiyan, M.; Navaneethakrishnan, K. R.; Gopalakrishnan, C.; Murugan, S. S.; Kumaravel, T. S. (Royal Society of Chemistry, 2015)
      Lanthanum oxide nanoparticles (LONP), a rare earth metal oxide, have unique properties that make them a suitable candidate for several biomedical applications. We investigated certain key in vitro and in vivo biocompatibility ...
    • Chiral ceramic nanoparticles and peptide catalysis 

      Jiang S.; Chekini, M.; Qu, Z.-B.; Wang Y.; Yeltik A.; Liu, Y.; Kotlyar, A.; Zhang, T.; Li, B.; Demir, H. V.; Kotov, N. A. (American Chemical Society, 2017)
      The chirality of nanoparticles (NPs) and their assemblies has been investigated predominantly for noble metals and II-VI semiconductors. However, ceramic NPs represent the majority of nanoscale materials in nature. The ...
    • Conjugated polymer nanoparticles 

      Tuncel, D.; Demir, H. V. (2010)
      Conjugated polymer nanoparticles are highly versatile nano-structured materials that can potentially find applications in various areas such as optoelectronics, photonics, bio-imaging, bio-sensing and nanomedicine. Their ...
    • Cornea engineering on polyester carriers 

      Zorlutuna, P.; Tezcaner, A.; Kiyat, I.; Aydinli, A.; Hasirci, V. (John Wiley & Sons, Inc., 2006)
      In this study, biodegradable polyester based carriers were designed for tissue engineering of the epithelial and the stromal layers of the cornea, and the final construct was tested in vitro. In the construction of the ...
    • Examination of fabrication conditions of acrylate-based hydrogel formulations for doxorubicin release and efficacy test for hepatocellular carcinoma cell 

      Bayramoglu, G.; Gozen, Damla; Ersoy, G.; Ozalp, V. C.; Akcali, K. C.; Arica, M. Y. (Taylor and Francis., 2014)
      The objective of the present study was to develop 2-hydroxypropyl methacrylate-co-polyethylene methacrylate [p(HPMA-co-PEG-MEMA)] hydrogels that are able to efficiently entrap doxorubicin for the application of loco-regional ...
    • Fabrication of polymer micro needles for transdermal drug delivery system using DLP based projection stereo-lithography 

      Ali, Z.; Türeyen, E. B.; Karpat, Y.; Çakmakcı, M. (Elsevier B.V., 2016)
      Fabrication of micro needles, which reduce pain during insertion and lessen tissue injury, has recently attracted great interest. Different manufacturing systems have been utilized for the advancement of micro needles such ...
    • Hierarchical self-assembly of histidine-functionalized peptide amphiphiles into supramolecular chiral nanostructures 

      Koc, M. H.; Ciftci, G. C.; Baday, S.; Castelletto, V.; Hamley, I. W.; Guler, M. O. (American Chemical Society, 2017)
      Controlling the hierarchical organization of self-assembling peptide amphiphiles into supramolecular nanostructures opens up the possibility of developing biocompatible functional supramolecular materials for various ...
    • Implantable microelectromechanical sensors for diagnostic monitoring and post-surgical prediction of bone fracture healing 

      McGilvray, K. C.; Ünal, E.; Troyer, K. L.; Santoni, B. G.; Palmer, R. H.; Easley, J. T.; Demir, H. V.; Puttlitz, C. M. (John Wiley and Sons Inc., 2015)
      The relationship between modern clinical diagnostic data, such as from radiographs or computed tomography, and the temporal biomechanical integrity of bone fracture healing has not been well-established. A diagnostic tool ...
    • In vitro biocompatibility of plasma-aided surface-modified 316L stainless steel for intracoronary stents 

      Bayram, C.; Mizrak, A.K.; Aktürk, S.; Kurşaklioǧlu H.; Iyisoy, A.; Ifran, A.; Denkbaş, E.B. (Institute of Physics Publishing, 2010)
      316L-type stainless steel is a raw material mostly used for manufacturing metallic coronary stents. The purpose of this study was to examine the chemical, wettability, cytotoxic and haemocompatibility properties of 316L ...
    • Inhibition of VEGF mediated corneal neovascularization by anti-angiogenic peptide nanofibers 

      Senturk, B.; Cubuk, M. O.; Ozmen, M. C.; Aydin B.; Guler, M. O.; Tekinay, A. B. (Elsevier, 2016-11)
      Atypical angiogenesis is one of the major symptoms of severe eye diseases, including corneal neovascularization, and the complex nature of abnormal vascularization requires targeted methods with high biocompatibility. The ...
    • Local delivery of doxorubicin through supramolecular peptide amphiphile nanofiber gels 

      Cinar, G.; Ozdemir, A.; Hamsici, S.; Gunay, G.; Dana, A.; Tekinay, A. B.; Guler, M. O. (Royal Society of Chemistry, 2017)
      Peptide amphiphiles (PAs) self-assemble into supramolecular nanofiber gels that provide a suitable environment for encapsulation of both hydrophobic and hydrophilic molecules. The PA gels have significant advantages for ...
    • Magnetic resonance imaging assisted by wireless passive implantable fiducial e-markers 

      Gokyar, S.; Alipour, A.; Unal, E.; Atalar, E.; Demir, H. V. (Institute of Electrical and Electronics Engineers, 2017)
      This paper reports a wireless passive resonator architecture that is used as a fiducial electronic marker (e-marker) intended for internal marking purposes in magnetic resonance imaging (MRI). As a proof-of-concept ...
    • Microfluidic device for synthesis of chitosan nanoparticles 

      Cetin, B.; Taze, S.; Asik, M.D.; Tuncel, S.A. (2013)
      Chitosan nanoparticles have a biodegradable, biocompatible, non-toxic structure, and commonly used for drug delivery systems. In this paper, simulation of a microfluidic device for the synthesis of chitosan nanoparticle ...
    • Nested metamaterials for wireless strain sensing 

      Melik, R.; Unal, E.; Perkgoz, N. K.; Santoni, B.; Kamstock, D.; Puttlitz, C.; Demir, H. V. (IEEE, 2009-12-28)
      We designed, fabricated, and characterized metamaterial-based RF-microelectromechanical system (RF-MEMS) strain sensors that incorporate multiple split ring resonators (SRRs) in a compact nested architecture to measure ...
    • One-Step Fabrication of Biocompatible Multifaceted Nanocomposite Gels and Nanolayers 

      Topuz, F.; Bartneck, M.; Pan, Y.; Tacke, F. (American Chemical Society, 2017)
      Nanocomposite gels are a fascinating class of polymeric materials with an integrative assembly of organic molecules and organic/inorganic nanoparticles, offering a unique hybrid network with synergistic properties. The ...
    • Peptide functionalized superparamagnetic iron oxide nanoparticles as MRI contrast agents 

      Sulek, S.; Mammadov, B.; Mahcicek, D. I.; Sozeri, H.; Atalar, E.; Tekinay, A. B.; Guler, M. O. (The Royal Society of Chemistry, 2011)
      Magnetic resonance imaging (MRI) attracts great attention in cellular and molecular imaging due to its non-invasive and multidimensional tomographic capabilities. Development of new contrast agents is necessary to enhance ...
    • Recent advances in bioactive 1D and 2D carbon nanomaterials for biomedical applications 

      Erol, O.; Uyan, I.; Hatip, M.; Yilmaz, C.; Tekinay, A. B.; Guler, M. O. (Elsevier, 2018)
      One-dimensional (1D) carbon nanotubes (CNTs) and the two-dimensional (2D) graphene represent the most widely studied allotropes of carbon. Due to their unique structural, electrical, mechanical and optical properties, 1D ...