Browsing by Author "Zhang, Q."

Now showing items 1-19 of 19

    • Autoantibodies against type I IFNs in patients with life-threatening COVID-19 

      Bastard, P.; Rosen, L. B.; Zhang, Q.; Michailidis, E.; Hoffmann, H.-H.; Zhang, Y.; Dorgham, K.; Philippot, Q.; Rosain, J.; Béziat, V.; Manry, J.; Shaw, E.; Haljasmägi, L.; Peterson, P.; Lorenzo, L.; Bizien, L.; Trouillet-Assant, S.; Dobbs, K.; Almeida de Jesus, A.; Belot, A.; Kallaste, A.; Catherinot, E.; Tandjaoui-Lambiotte, Y.; Le Pen, J.; Kerner, G.; Bigio, B.; Seeleuthner, Y.; Yang, R.; Bolze, A.; Spaan, A. N.; Delmonte, O. M.; Abers, M. S.; Aiuti, A.; Casari, G.; Lampasona, V.; Piemonti, L.; Ciceri, F.; Bilguvar, K.; Lifton, R. P.; Vasse, M.; Smadja, D. M.; Migaud, M.; Hadjadj, J.; Terrier, B.; Duffy, D.; Quintana-Murci, L.; van de Beek, D.; Roussel, L.; Vinh, D. C.; Tangye, S. G.; Haerynck, F.; Dalmau, D.; Martinez-Picado, J.; Brodin, P.; Nussenzweig, M. C.; Boisson-Dupuis, S.; Rodríguez-Gallego, C.; Vogt, G.; Mogensen, T. H.; Oler, A. J.; Gu, J.; Burbelo, P. D.; Cohen, J. I.; Biondi, A.; Bettini, L. R.; D'Angio, M.; Bonfanti, P.; Rossignol, P.; Mayaux, J.; Rieux-Laucat, F.; Husebye, E. S.; Fusco, F.; Ursini, M. V.; Imberti, L.; Sottini, A.; Paghera, S.; Quiros-Roldan, E.; Rossi, C.; Castagnoli, R.; Montagna, D.; Özçelik, Tayfun; Licari, A.; Marseglia, G. L.; Duval, X.; Ghosn, J.; Tsang, J. S.; Goldbach-Mansky, R.; Kisand, K.; Lionakis, M. S.; Puel, A.; Zhang, S.- Y.; Holland, S. M.; Gorochov, G.; Jouanguy, E.; Rice, C. M.; Cobat, A.; Notarangelo, L. D.; Abel, L.; Su, H. C.; Casanova, J. L.; HGID Lab; NIAID-USUHS Immune Response to COVID Group; COVID Clinicians; COVID-STORM Clinicians; Imagine COVID Group; French COVID Cohort Study Group; Milieu Intérieur Consortium; CoV-Contact Cohort; Amsterdam UMC Covid-19 Biobank; COVID Human Genetic Effort (2020)
      Interindividual clinical variability in the course of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is vast. We report that at least 101 of 987 patients with life-threatening coronavirus disease ...

    • Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths 

      Bastard, P.; Gervais, A.; Le Voyer, T.; Rosain, J.; Philippot, Q.; Manry, J.; Michailidis, E.; Hoffmann, H. H.; Eto, S.; Garcia-Prat, M.; Bizien, L.; Parra-Martinez, A.; Yang, R.; Haljasmagi, L.; Migaud, M.; Sarekannu, K.; Maslovskaja, J.; de Prost, N.; Tandjaoui-Lambiotte, Y.; Luyt, C. E.; Amador-Borrero, B.; Gaudet, A.; Poissy, J.; Morel, P.; Richard, P.; Cognasse, F.; Troya, J.; Trouillet-Assant, S.; Belot, A.; Saker, K.; Garcon, P.; Riviere, J. G.; Lagier, J. C.; Gentile, S.; Rosen, L. B.; Shaw, E.; Morio, T.; Tanaka, J.; Dalmau, D.; Tharaux, PL.; Sene, D.; Stepanian, A.; Megarbane, B.; Triantafyllia, V.; Fekkar, A.; Heath, J. R.; Franco, JL.; Anaya, J. M.; Sole-Violan, J.; Imberti, L.; Biondi, A.; Bonfanti, P.; Castagnoli, R.; Delmonte, O. M.; Zhang, Y.; Snow, A. L.; Holland, S. M.; Biggs, C. M.; Moncada-Velez, M.; Arias, A. A.; Lorenzo, L.; Boucherit, S.; Coulibaly, B.; Anglicheau, D.; Planas, A. M.; Haerynck, F.; Duvlis, S.; Nussbaum, R. L.; Özçelik, Tayfun; Keles, S.; Bousfiha, A. A.; El Bakkouri, J.; Ramirez-Santana, C.; Paul, S.; Pan-Hammarstrom, Q.; Hammarstrom, L.; Dupont, A.; Kurolap, A.; Metz, CN.; Aiuti, A.; Casari, G.; Lampasona, V.; Ciceri, F.; Barreiros, L. A.; Dominguez-Garrido, E.; Vidigal, M.; Zatz, M.; van de Beek, D.; Sahanic, S.; Tancevski, I.; Stepanovskyy, Y.; Boyarchuk, O.; Nukui, Y.; Tsumura, M.; Vidaur, L.; Tangye, S. G.; Burrel, S.; Duffy, D.; Quintana-Murci, L.; Klocperk, A.; Kann, N. Y.; Shcherbina, A.; Lau, Y. L.; Leung, D.; Coulongeat, M.; Marlet, J.; Koning, R.; Reyes, L. F.; Chauvineau-Grenier, A.; Venet, F.; Monneret, G.; Nussenzweig, MC.; Arrestier, R.; Boudhabhay, I.; Baris-Feldman, H.; Hagin, D.; Wauters, J.; Meyts, I.; Dyer, A. H.; Kennelly, SP.; Bourke, N. M.; Halwani, R.; Sharif-Askari, N. S.; Dorgham, K.; Sallette, J.; Sedkaoui, S. M.; AlKhater, S.; Rigo-Bonnin, R.; Morandeira, F.; Roussel, L.; Vinh, DC.; Ostrowski, SR.; Condino-Neto, A.; Prando, C.; Bondarenko, A.; Spaan, A. N.; Gilardin, L.; Fellay, J.; Lyonnet, S.; Bilguvar, K.; Lifton, R. P.; Mane, S.; Anderson, M. S.; Boisson, B.; Beziat, V.; Zhang, SY.; Andreakos, E.; Hermine, O.; Pujol, A.; Peterson, P.; Mogensen, T. H.; Rowen, L.; Mond, J.; Debette, S.; de Lamballerie, X.; Duval, X.; Mentre, F.; Zins, M.; Soler-Palacin, P.; Colobran, R.; Gorochov, G.; Solanich, X.; Susen, S.; Martinez-Picado, J.; Raoult, D.; Vasse, M.; Gregersen, P. K.; Piemonti, L.; Rodriguez-Gallego, C.; Notarangelo, LD.; Su, H. C.; Kisand, K.; Okada, S.; Puel, A.; Jouanguy, E.; Rice, C. M.; Tiberghien, P.; Zhang, Q.; Cobat, A.; Abel, L.; Casanova, J. L. (American Association for the Advancement of Science (AAAS), 2021-08-20)
      Circulating autoantibodies (auto-Abs) neutralizing high concentrations (10 ng/ml; in plasma diluted 1:10) of IFN-α and/or IFN-ω are found in about 10% of patients with critical COVID-19 (coronavirus disease 2019) pneumonia ...

    • Biomarker-guided sequential targeted therapies to overcome therapy resistance in rapidly evolving highly aggressive mammary tumors 

      Sahin, O.; Wang, Q.; Brady, S. W.; Ellis, K.; Wang, H.; Chang, C. C.; Zhang, Q.; Priya, P.; Zhu, R.; Wong, S. T.; Landis, M. D.; Muller, W. J.; Esteva, F. J.; Chang, J.; Yu, D. (Nature Publising Group, 2014)
      Combinatorial targeted therapies are more effective in treating cancer by blocking by-pass mechanisms or inducing synthetic lethality. However, their clinical application is hampered by resistance and toxicity. To meet ...

    • The COST292 experimental framework for TRECVID 2007 

      Zhang, Q.; Corvaglia, M.; Aksoy, Selim; Naci, U.; Adami, N.; Aginako, N.; Alatan, A.; Alexandre, L. A.; Almeida, P.; Avrithis, Y.; Benois-Pineau, J.; Chandramouli, K.; Damnjanovic, U.; Esen, E.; Goya, J.; Grzegorzek, M.; Hanjalic, A.; Izquierdo, E.; Jarina, R.; Kapsalas, P.; Kompatsiaris, I.; Kuba, M.; Leonardi, R.; Makris, L.; Mansencal, B.; Mezaris, V.; Moumtzidou, A.; Mylonas, P.; Nikolopoulos, S.; Piatrik, T.; Pinheiro, A. M. G.; Reljin, B.; Spyrou, E.; Tolias, G.; Vrochidis, S.; Yakın, G.; Zajic, G. (National Institute of Standards and Technology, 2007)
      In this paper, we give an overview of the four tasks submitted to TRECVID 2007 by COST292. In shot boundary (SB) detection task, four SB detectors have been developed and the results are merged using two merging algorithms. ...

    • Dye-sensitized solar cell with a pairof carbon-based electrodes 

      Kyaw, A. K. K.; Tantang, H.; Wu, T.; Ke, L.; Wei, J.; Demir, Hilmi Volkan; Zhang, Q.; Sun, X. W. (IOP Publishing, 2012-04-02)
      We have fabricated a dye-sensitized solar cell (DSSC) with a pair of carbon-based electrodes using a transparent, conductive carbon nanotubes (CNTs) film modified with ultra-thin titanium-sub-oxide (TiOx) as the working ...

    • Dye-sensitized solar cell with a titanium-oxide-modified carbon nanotube transparent electrode 

      Kyaw, A. K. K.; Tantang, H.; Wu, T.; Ke, L.; Peh, C.; Huang, Z. H.; Zeng, X. T.; Demir, Hilmi Volkan; Zhang, Q.; Sun, X. W. (American Institute of Physics, 2011-07-15)
      Transparent and conductive carbon-based materials are promising for window electrodes in solid-state optoelectronic devices. However, the catalytic activity to redox reaction limits their application as a working electrode ...

    • Excitonics of semiconductor quantum dots and wires for lighting and displays 

      Guzelturk, B.; Martinez, P. L. H.; Zhang, Q.; Xiong, Q.; Sun, H.; Sun, X. W.; Govorov, A. O.; Demir, Hilmi Volkan (Wiley-VCH Verlag, 2013)
      In the past two decades, semiconductor quantum dots and wires have developed into new, promising classes of materials for next-generation lighting and display systems due to their superior optical properties. In particular, ...

    • Fluorophore-doped core-multishell spherical plasmonic nanocavities: resonant energy transfer towards a loss compensation 

      Peng, B.; Zhang, Q.; Liu, X.; Ji Y.; Demir, Hilmi Volkan; Huan, C. H. A.; Sum, T. C.; Wiong, Q. (American Chemical Society, 2012-06-12)
      Plasmonics exhibits the potential to break the diffraction limit and bridge the gap between electronics and photonics by routing and manipulating light at the nanoscale. However, the inherent and strong energy dissipation ...

    • A global effort to define the human genetics of protective immunity to SARS-CoV-2 infection 

      Casanova, J.-L.; Su, H. C.; Abel, L.; Aiuti, A.; Almuhsen, S.; Arias, A. A.; Bastard, P.; Biggs, C.; Bogunovic, D.; Boisson, B.; Boisson-Dupuis, S.; Bolze, A.; Bondarenko, A.; Bousfiha, A.; Brodin, P.; Bustamante, J.; Butte, M.; Casari, G.; Ciancanelli, M.; Cobat, A.; Condino-Neto, A.; Cooper, M.; Dalgard, C.; Espinosa, S.; Feldman, H.; Fellay, J.; Franco, J. L.; Hagin, D.; Itan, Y.; Jouanguy, E.; Lucas, C.; Mansouri, D.; Meyts, I.; Milner, J.; Mogensen, T.; Morio, T.; Ng, L.; Notarangelo, L. D.; Okada, S.; Özçelik, Tayfun; Palacín, P. S.; Planas, A.; Prando, C.; Puel, A.; Pujol, A.; Redin, C.; Renia, L.; Gallego, J. C. R.; Quintana-Murci, L.; Sancho-Shimizu, V.; Sankaran, V.; Seppänen, M. R. J.; Shahrooei, M.; Snow, A.; Spaan, A.; Tangye, S.; Tur, J. P.; Turvey, S.; Vinh, D. C.; von Bernuth, H.; Wang, X.; Zawadzki, P.; Zhang, Q.; Zhang, S. (Elsevier, 2020)
      SARS-CoV-2 infection displays immense inter-individual clinical variability, ranging from silent infection to lethal disease. The role of human genetics in determining clinical response to the virus remains unclear. Studies ...

    • High-efficiency light-emitting diodes of organometal halide perovskite amorphous nanoparticles 

      Xing, J.; Yan, F.; Zhao Y.; Chen, S.; Yu, H.; Zhang, Q.; Zeng, R.; Demir, Hilmi Volkan; Sun, X.; Huan, A.; Xiong, Q. (American Chemical Society, 2016)
      Organometal halide perovskite has recently emerged as a very promising family of materials with augmented performance in electronic and optoelectronic applications including photovoltaic devices, photodetectors, and ...

    • Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 

      Zhang, Q.; Liu, Z.; Moncada-Velez, M.; Chen, J.; Ogishi, M.; Bigio, B.; Yang, R.; Arias, A. A.; Zhou, Q.; Han, J. E.; Özçelik, Tayfun; Uğurbil, A. C.; Zhang, P.; Rapaport, F.; Li, J.; Spaan, A. N. (American Association for the Advancement of Science, 2020)
      Clinical outcomes of human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection range from silent infection to lethal coronavirus disease 2019 (COVID-19). Epidemiological studies have identified three ...

    • Observation of selective plasmon-exciton coupling in nonradiative energy transfer: donor-selective versus acceptor-selective plexcitons 

      Ozel, T.; Hernandez-Martinez, P. L.; Mutlugun, E.; Akin, O.; Nizamoglu, S.; Ozel, I. O.; Zhang, Q.; Xiong, Q.; Demir, Hilmi Volkan (American Chemical Society, 2013-06)
      We report selectively plasmon-mediated nonradiative energy transfer between quantum dot (QD) emitters interacting with each other via Forster-type resonance energy transfer (FRET) under controlled plasmon coupling either ...

    • Oligomerization of ethylene in a slurry reactor using a nickel/sulfated alumina catalyst 

      Zhang, Q.; Kantcheva, M.; Dalla Lana, I. G. (American Chemical Society, 1997)
      During the oligomerization of ethylene over heterogeneous catalysts, the production of α-olefins may be lowered because of an accompanying deactivation of catalyst resulting from strong adsorption of products, by isomerization ...

    • Quantum dots on vertically aligned gold nanorod monolayer: plasmon enhanced fluorescence 

      Peng, B.; Li, Z.; Mutlugun, E.; Martinez, P. L. H.; Li, D.; Zhang, Q.; Gao, Y.; Demir, Hilmi Volkan; Xiong, Q. (Royal Society of Chemistry, 2014)
      CTAB-coated Au nanorods were directly self-assembled into a vertically aligned monolayer with highly uniform hot spots through a simple but robust approach. By coupling with CdSe/ZnS quantum dots, a maximum enhancement of ...

    • State of the art and prospects for Halide Perovskite nanocrystals 

      Dey, A.; Ye, J.; De, A.; Debroye, E.; Ha, S. K.; Bladt, E.; Kshirsagar, A. S.; Wang, Z.; Yin, J.; Wang, Y.; Quan, L. N.; Yan, F.; Gao, M.; Li, X.; Shamsi, J.; Debnath, T.; Cao, M.; Scheel, M. A.; Kumar, S.; Steele, J. A.; Gerhard, M.; Chouhan, L.; Xu, K.; Wu, X-g; Li, Y.; Zhang, Y.; Han, C.; Dutta, A.; Vincon, I.; Rogach, A. L.; Nag, A.; Samanta, A.; Korgel, B. A.; Shih, C.-J.; Gamelin, D. R.; Son, D. H.; Zeng, H.; Zhong, H.; Sun, H.; Demir, Hilmi Volkan; Scheblykin, I. G.; Mora-Seró, I.; Stolarczyk, J. K.; Zhang, J. Z.; Feldmann, J.; Hofkens, J.; Luther, J. M.; Pérez-Prieto, J.; Li, L.; Manna, L.; Bodnarchuk, M. I.; Kovalenko, M. V.; Roeffaers, M. B. J.; Pradhan, N.; Mohammed, O. F.; Bakr, O. M.; Yang, P.; Müller-Buschbaum, P.; Kamat, P. V.; Bao, Q.; Zhang, Q.; Krahne, R.; Galian, R. E.; Stranks, S. D.; Bals, S.; Biju, V.; Tisdale, W. A.; Yan, Y.; Hoye, R. L. Z.; Polavarapu, L. (American Chemical Society, 2021-06-17)
      Metal-halide perovskites have rapidly emerged as one of the most promising materials of the 21st century, with many exciting properties and great potential for a broad range of applications, from photovoltaics to optoelectronics ...

    • Tuberculosis and impaired IL-23-dependent IFN-γ immunity in humans homozygous for a common TYK2 missense variant 

      Boisson-Dupuis, S.; Ramirez-Alejo, N.; Li, Z.; Patin, E.; Rao, G.; Kerner, G.; Lim, C. K.; Krementsov, D. N.; Hernandez, N.; Ma, C. S.; Zhang, Q.; Markle, J.; Martinez-Barricarte, R.; Payne, K.; Fisch, R.; Deswarte, C.; Halpern, J.; Bouaziz, M.; Mulwa, J.; Sivanesan, D.; Lazarov, T.; Naves, R.; Garcia, P.; Itan, Y.; Boisson, B.; Checchi, A.; Jabot-Hanin, F.; Cobat, A.; Guennoun, A.; Jackson, C. C.; Pekcan, S.; Çalışkaner, Z.; Inostroza, J.; Costa-Carvalho, B. T.; De Albuquerque, J. A. T.; Garcia-Ortiz, H.; Orozco, L.; Özçelik, Tayfun; Abid, A.; Rhorfi, I. A.; Souhi, H.; Amrani, H. N.; Zegmout, A.; Geissmann, F.; Michnick, S. W.; Muller-Fleckenstein, I.; Fleckenstein, B.; Puel, A.; Ciancanelli, M. J.; Marr, N.; Abolhassani, H.; Balcells, M. E.; Condino-Neto, A.; Strickler, A.; Abarca, K.; Teuscher, C.; Ochs, H. D.; Reisli, I.; Sayar, E. H.; El-Baghdadi, J.; Bustamante, J.; Hammarström, L.; Tangye, S. G.; Pellegrini, S.; Quintana-Murci, L.; Abel, L.; Casanova, J. -L. (NLM (Medline), 2018)
      Inherited IL-12Rβ1 and TYK2 deficiencies impair both IL-12- and IL-23-dependent IFN-γ immunity and are rare monogenic causes of tuberculosis, each found in less than 1/600,000 individuals. We show that homozygosity for the ...

    • Upregulation of lactate dehydrogenase a by 14-3-3ζ leads to increased glycolysis critical for breast cancer initiation and progression 

      Chang, C.; Zhang, C.; Zhang, Q.; Sahin, O.; Wang, H.; Xu, J.; Xiao, Y.; Zhang, J.; Rehman, S. K.; Li, P.; Hung, M. C.; Behbod, F.; Yu, D. (Impact Journals LLC, 2016-05)
      Metabolic reprogramming is a hallmark of cancer. Elevated glycolysis in cancer cells switches the cellular metabolic flux to produce more biological building blocks, thereby sustaining rapid proliferation. Recently, new ...

    • Vertically aligned gold nanorod monolayer on arbitrary substrates: self-assembly and femtomolar detection of food contaminants 

      Peng, B.; Li, G.; Li, D.; Dodson, S.; Zhang, Q.; Zhang, J.; Lee, Y. H.; Demir, Hilmi Volkan; Ling, X. Y.; Xiong, Q. (American Chemical Society, 2013)
      Public attention to the food scandals raises an urgent need to develop effective and reliable methods to detect food contaminants. The current prevailing detections are primarily based upon liquid chromatography, mass ...

    • X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19 

      Asano, T.; Boisson, B.; Onodi, F.; Matuozzo, D.; Moncada-Velez, M.; Renkilaraj, M. R. L. M.; Zhang, P.; Meertens, L.; Bolze, A.; Materna, M.; Korniotis, S.; Gervais, A.; Talouarn, E.; Bigio, B.; Seeleuthner, Y.; Bilguvar, K.; Zhang, Y.; Neehus, AL.; Ogishi, M.; Pelham, SJ.; Le Voyer, T.; Rosain, J.; Philippot, Q.; Soler-Palacin, P.; Colobran, R.; Martin-Nalda, A.; Riviere, J. G.; Tandjaoui-Lambiotte, Y.; Chaibi, K.; Shahrooei, M.; Darazam, I. A.; Olyaei, NA.; Mansouri, D.; Palabiyik, F.; Özçelik, Tayfun; Novelli, G.; Novelli, A.; Casari, G.; Aiuti, A.; Carrera, P.; Bondesan, S.; Barzaghi, F.; Rovere-Querini, P.; Tresoldi, C.; Franco, J. L.; Rojas, J.; Reyes, LF.; Bustos, IG.; Arias, AA.; Morelle, G.; Kyheng, C.; Troya, J.; Planas-Serra, L.; Schluter, A.; Gut, M.; Pujol, A.; Allende, L. M.; Rodriguez-Gallego, C.; Flores, C.; Cabrera-Marante, O.; Pleguezuelo, DE.; de Diego, R. P.; Keles, S.; Aytekin, G.; Akcan, O. M.; Bryceson, Y. T.; Bergman, P.; Brodin, P.; Smole, D.; Smith, C. I. E.; Norlin, A. C.; Campbell, T. M.; Covill, LE.; Hammarstrom, L.; Pan-Hammarstrom, Q.; Abolhassani, H.; Mane, S.; Marr, N.; Ata, M.; Al Ali, F.; Khan, T.; Spaan, A. N.; Dalgard, C. L.; Bonfanti, P.; Biondi, A.; Tubiana, S.; Burdet, C.; Nussbaum, R.; Kahn-Kirby, A.; Snow, AL.; Bustamante, J.; Puel, A.; Boisson-Dupuis, S.; Zhang, S. Y.; Beziat, V.; Lifton, R. P.; Bastard, P.; Notarangelo, L. D.; Abel, L.; Su, H. C.; Jouanguy, E.; Amara, A.; Soumelis, V.; Cobat, A.; Zhang, Q.; Casanova, J. L. (American Association for the Advancement of Science (AAAS), 2021-08-20)
      Autosomal inborn errors of type I IFN immunity and autoantibodies against these cytokines underlie at least 10% of critical COVID-19 pneumonia cases. We report very rare, biochemically deleterious X-linked TLR7 variants ...