Browsing by Author "Yıldız, Gökhan"
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Differential expression of epigenetic regulatory genes in liver cancer
Yıldız, Gökhan; Öztürk, Mehmet (International Liver Cancer Association, 2012-09)Epigenetic mechanisms are involved in the organization of chromatin structure and global regulation of gene expression [1]. Cancer cells display multiple epigenetic changes including aberrations in the methylation of DNA, ... -
Genetics and epigenetics of liver cancer
Özen, Çiğdem; Yıldız, Gökhan; Dağcan, Alper Tunga; Çevik, Dilek; Örs, Ayşegül; Keleş, Umut; Topel, Hande; Öztürk, Mehmet (Elsevier, 2013)Hepatocellular carcinoma (HCC) represents a major form of primary liver cancer in adults. Chronic infections with hepatitis B (HBV) and C (HCV) viruses and alcohol abuse are the major factors leading to HCC. This deadly ... -
Roles of senescence escape and epigenetic modifications in liver cancer
Yıldız, Gökhan (Bilkent University, 2013)Development of hepatocellular carcinoma (HCC) is a multi-step progressive process in which a healthy liver transforms into cancerous tissue. Senescence is a permanent proliferation arrest in response to cell stress such ...