Now showing items 1-3 of 3

    • Differential expression of epigenetic regulatory genes in liver cancer 

      Yıldız, Gökhan; Öztürk, Mehmet (International Liver Cancer Association, 2012-09)
      Epigenetic mechanisms are involved in the organization of chromatin structure and global regulation of gene expression [1]. Cancer cells display multiple epigenetic changes including aberrations in the methylation of DNA, ...
    • Genetics and epigenetics of liver cancer 

      Özen, Çiğdem; Yıldız, Gökhan; Dağcan, Alper Tunga; Çevik, Dilek; Örs, Ayşegül; Keleş, Umut; Topel, Hande; Öztürk, Mehmet (Elsevier, 2013)
      Hepatocellular carcinoma (HCC) represents a major form of primary liver cancer in adults. Chronic infections with hepatitis B (HBV) and C (HCV) viruses and alcohol abuse are the major factors leading to HCC. This deadly ...
    • Roles of senescence escape and epigenetic modifications in liver cancer 

      Yıldız, Gökhan (Bilkent University, 2013)
      Development of hepatocellular carcinoma (HCC) is a multi-step progressive process in which a healthy liver transforms into cancerous tissue. Senescence is a permanent proliferation arrest in response to cell stress such ...