Browsing by Author "Weiner, J. L."

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Growth hormone and insulin-like growth factor-I alter hippocampal excitatory synaptic transmission in young and old rats

Molina, D. P.; Ariwodola, O. J.; Weiner, J. L.; Bechtold, J. K. B.; Adams, Michelle M. (Age Company, 2013)

In rats, as in humans, normal aging is characterized by a decline in hippocampal-dependent learning and memory, as well as in glutamatergic function. Both growth hormone (GH) and insulin-like growth factor-I (IGF-I) levels ...
Growth hormone modulates hippocampal excitatory synaptic transmission and plasticity in old rats

Molina, D. P.; Ariwodola, O. J.; Linville, C.; Sonntag, W. E.; Weiner, J. L.; Brunso-Bechtold, J. K.; Adams, Michelle M. (Elsevier, 2012)

Alterations in the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor (AMPA-R) and N-methyl-D-aspartate receptor (NMDA-R) have been documented in aged animals and may contribute to changes in hippocampal-dependent ...