Browsing by Author "Topal, Ahmet E."
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Biocompatible electroactive tetra (aniline)-conjugated peptide nanofibers for neural differentiation
Arioz, Idil; Erol, Ozlem; Bakan, Gokhan; Dikecoglu, F. Begum; Topal, Ahmet E.; Urel, Mustafa; Dana, Aykutlu; Tekinay, Ayse B.; Güler, Mustafa O. (American Chemical Society, 2018)Peripheral nerve injuries cause devastating problems for the quality of patients' lives, and regeneration following damage to the peripheral nervous system is limited depending on the degree of the damage. Use of ... -
Biosensors for early disease diagnosis
Topal, Ahmet E.; Özkan, Alper Devrim; Dana, Aykutlu; Tekinay, Ayse B.; Güler, Mustafa O. (John Wiley & Sons, 2016-03-11)This chapter focuses on biosensor types, their detection limits, analysis times, and the diseases they are suitable for detecting. In addition, as nanomaterials are an effective means of producing small‐scale diagnostic ... -
A modular antigen presenting peptide/oligonucleotide nanostructure platform for inducing potent immune response
Tohumeken, Sehmus; Gunduz, Nuray; Demircan, M. Burak; Gunay, Gokhan; Topal, Ahmet E.; Khalily, M. Aref; Tekinay, T.; Dana, Aykutlu; Güler, Mustafa O.; Tekinay, Ayse B. (Wiley - VCH Verlag GmbH & Co. KGaA, 2017-05)The design and development of vaccines, which can induce cellular immunity, particularly CD8+ T cells hold great importance since these cells play crucial roles against cancers and viral infections. Covalent conjugation ... -
Supramolecular peptide nanofiber morphology affects mechanotransduction of stem cells
Arslan, Elif; Koc,, Meryem Hatip; Uysal, Ozge; Dikecoglu, Begum; Topal, Ahmet E.; Garifullin, Ruslan; Ozkan, Alper D.; Dana, A.; Hermida-Merino, D.; Castelletto, V.; Edwards-Gayle, C.; Baday, S.; Hamley, I.; Tekinay, Ayse B.; Güler, Mustafa O. (American Chemical Society, 2017-08)Chirality and morphology are essential factors for protein function and interactions with other biomacromolecules. Extracellular matrix (ECM) proteins are also similar to other proteins in this sense; however, the complexity ...