Browsing by Author "Tekinay, Ayşe B."
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Advances in nanoparticle‐based medical diagnostic and therapeutic techniques
Sardan, Melis; Özkan, Alper Devrim; Zengin, Aygül; Tekinay, Ayşe B.; Güler, Mustafa O. (John Wiley & Sons, 2016-03-11)Advances in modern medicine have eliminated several major causes of human mortality and considerably extended life expectancies around the world; however, this increase in the global age average has also boosted the ... -
Bioactive peptide amphiphile nanofibers for cornea regeneration
Uzunallı, Gözde; Soran, Zeliha; Dağtaş, Yavuz S.; Aydın, B.; Güler, Mustafa O.; Tekinay, Ayşe B. (John Wiley & Sons, 2012) -
Bioactive self-assembled peptide nanofibers for corneal stroma regeneration
Uzunallı, Gözde; Soran, Zeliha Soran; Erkal, Turan S.; Dagdas, Yavuz S; Dinc, E.; Hondur, A. M.; Bilgihan, K.; Aydin B.; Güler, Mustafa O.; Tekinay, Ayşe B. (Elsevier, 2014)Defects in the corneal stroma caused by trauma or diseases such as macular corneal dystrophy and keratoconus can be detrimental for vision. Development of therapeutic methods to enhance corneal regeneration is essential ... -
Biotin functionalized self‐assembled peptide nanofiber as an adjuvant for immunomodulatory response
Demircan, Muhammed Burak; Tohumeken, Sehmus; Gündüz, Nuray; Khalily, Mohammad Aref; Tekinay, T.; Güler, M. O.; Tekinay, Ayşe B. (Wiley-VCH Verlag, 2020-12)Biotinylated peptide amphiphile (Biotin‐PA) nanofibers, are designed as a noncovalent binding location for antigens, which are adjuvants to enhance, accelerate, and prolong the immune response triggered by antigens. ... -
Collagen peptide presenting nanofibrous scaffold for intervertebral disc regeneration
Uysal, Özge; Arslan, Elif; Gülseren, Gülcihan; Kılınç, M. C.; Doğan, İ.; Özalp, H.; Çağlar, Y. Ş.; Güler, M. O.; Tekinay, Ayşe B. (American Chemical Society, 2019)Lower back pain (LBP) is a prevalent spinal symptom at the lumbar region of the spine, which severely effects quality of life and constitutes the number one cause of occupational disability. Degeneration of the intervertebral ... -
Extracellular matrix mimetic peptide scaffolds for neural stem cell culture and differentiation
Mammadov, Busra; Güler, Mustafa O.; Tekinay, Ayşe B. (Humana Press, 2014)Self-assembled peptide nanofibers form three-dimensional networks that are quite similar to fibrous extracellular matrix (ECM) in their physical structure. By incorporating short peptide sequences derived from ECM proteins, ... -
Extracellular-matrix mimetic peptide nanofibers for neural regenerative medicine
Tekinay, Ayşe B.; Mammadov, B. (John Wiley & Sons, 2012) -
Generation of chimeric "aBS nanohemostat" complex and comparing its histomorphological in vivo effects to the traditional ankaferd hemostat in controlled experimental partial nephrectomy model
Huri, Emre; Beyazit, Y.; Mammadov, Rashad; Toksoz, Sıla; Tekinay, Ayşe B.; Güler, Mustafa O.; Ustun H.; Kekilli, M.; Dadali, Mumtaz; Celik, T.; Astarci, M.; Haznedaroglu I.C. (Hindawi, 2013)Purpose. Using the classical Ankaferd Blood Stopper (ABS) solution to create active hemostasis during partial nephrectomy (PN) may not be so effective due to insufficient contact surface between the ABS hemostatic liquid ... -
Growth and differentiation of pre-chondrogenic ATDC5 cells on bioactive self-assembled peptide nanofibers
Üstün, Seher; Tombuloğlu, Ayşe; Uzunallı, Gözde; Güler, Mustafa O.; Tekinay, Ayşe B. (John Wiley & Sons, 2012) -
Growth and differentiation of prechondrogenic cells on bioactive self-assembled peptide nanofibers
Üstün, Seher; Tombuloğlu, Ayşegül; Kılınç, Murat; Güler, Mustafa O.; Tekinay, Ayşe B. (American Chemical Society, 2013)Restoration of cartilage defect remains a challenge, as the current treatments are ineffective to return tissue to its health. Thus, developing therapies for treatment of cartilage tissue damage caused by common joint ... -
Growth factor binding on heparin mimetic peptide nanofibers
Mammadov, Rashad; Mammadov, Busra; Güler, Mustafa O.; Tekinay, Ayşe B. (American Chemical Society, 2012)Immobilization of growth factors in scaffolds is important for controlling their dose and bioactivity for regenerative medicine applications. Although numerous covalent and noncovalent immobilization strategies have been ... -
Heparin mimetic peptide amphiphile nanofibers for angiogenesis
Soran, Zeliha; Uzunallı, Gözde; Dağtaş, Yavuz S.; Tekinay, Ayşe B.; Güler, Mustafa O. (John Wiley & Sons, 2012) -
Materials for articular cartilage regeneration
Tombuloglu, Ayşegül; Tekinay, Ayşe B.; Güler, Mustafa O. (Bentham Science Publishers B.V., 2012)Many health problems remaining to be untreatable throughout the human history can be overcome by utilizing new biomedical materials. Healing cartilage defects is one of the problems causing significant health issue due to ... -
Mechanical properties of self-assembling peptide hydrogels and their effects on cell behaviors
Çınar, Göksu; Ceylan, Hakan; Tekinay, Ayşe B.; Güler, Mustafa O. (John Wiley & Sons, 2012) -
Mitochondrial serine protease HTRA2 p.G3999S in a kindred with essential tremor and Parkinson disease
Gülümser, Hilal Ünal; Gulsuner, S.; Mercan, F. N.; Onat, Onur Emre; Walsh, T.; Shahin, H.; Lee, M. K.; Dogu, O.; Kansu, T.; Topaloglu, H.; Elibol, B.; Akbostanci, C.; King, M. C.; Özçelik, Tayfun; Tekinay, Ayşe B. (National Academy of Sciences, 2014)Essential tremor is one of the most frequent movement disorders of humans and can be associated with substantial disability. Some but not all persons with essential tremor develop signs of Parkinson disease, and the ... -
Multifunctional peptide nanofiber scaffolds for neural differentiation
Mammadov, B.; Erkal, Turhan Selman; Ürel, Mustafa; Güler, Mustafa O.; Tekinay, Ayşe B. (John Wiley & Sons, 2012) -
Mussel-inspired functionalization of metal surfaces with bioactive self-assembled peptide nanofibers
Ceylan, Hakan; Kocabey, Samet; Güler, Mustafa O.; Tekinay, Ayşe B. (John Wiley & Sons, 2012) -
N-cadherin mimetic peptide nanofiber system induces chondrogenic differentiation of mesenchymal stem cells
Çimenci, Çağla Eren; Uzunalli-Kurtuluş, G.; Çalışkan, Özüm S.; Güler, M. O.; Tekinay, Ayşe B. (American Chemical Society, 2019)Cadherins are vital for cell-to-cell interactions during tissue growth, migration, and differentiation processes. Both biophysical and biochemical inputs are generated upon cell-to-cell adhesions, which determine the fate ... -
Nanomaterials as tissue adhesives
Yasa, İ. Ceren; Ceylan, Hakan; Tekinay, Ayşe B.; Güler, Mustafa O. (John Wiley & Sons, 2016-03-11)Tissue adhesives are used to create functional bonding interfaces between injured tissue parts and between tissues and implanted biomaterials. This chapter provides a critical review of the conventional tissue adhesive ... -
Nanomaterials for bone tissue regeneration and orthopedic implants
Gülseren, Gülcihan; Ceylan, Hakan; Tekinay, Ayşe B.; Güler, Mustafa O. (John Wiley & Sons, 2016-03-11)Hierarchical organization and specialized composition of bone extracellular matrix (ECM) control the cellular processes including proliferation, migration, and differentiation for continuous modulation and maintenance of ...