Browsing by Author "Riddle, D."

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Caloric restriction eliminates the aging-related decline in NMDA and AMPA receptor subunits in the rat hippocampus and induces homeostasis

Shi, L.; Adams, Michelle M.; Linville, M.; Newton, I.; Forbes, M.; Long, A.; Riddle, D.; Brunso-Bechtold, J. (ElsevierAysel Sabuncu Brain Research Center (BAM), 2007)

Caloric restriction (CR) extends life span and ameliorates the aging-related decline in hippocampal-dependent cognitive function. In the present study, we compared subunit levels of NMDA and AMPA types of the glutamate ...
Stability of local brain levels of insulin-like growth factor-I in two well-characterized models of decreased plasma IGF-I

Adams, Michelle M.; Forbes, M; Linville, M.; Riddle, D.; Sonntag, W.; Brunso-Bechtold, J. (Taylor & Francis, 2009)

Insulin-like growth factor-I (IGF-I), a functionally important neurotrophic factor, impacts tissues throughout the body including the central nervous system. In addition to the significant proportion of IGF-I that is ...