Now showing items 1-6 of 6

    • Discovering competing endogenous RNA interactions in breast cancer molecular subtypes 

      Olgun, Gülden; Şahin, Özgür; Taştan, Öznur (Springer, 2018)
      Background: Long non-coding RNAs (lncRNAs) can indirectly regulate mRNAs expression levels by sequestering microRNAs (miRNAs), and act as competing endogenous RNAs (ceRNAs) or as sponges. Previous studies identified ...
    • Discovering regulatory non-coding RNA interactions 

      Olgun, Gülden (Bilkent University, 2019-09)
      The vast majority of eukaryotic transcriptomes comprise noncoding RNAs (ncRNAs) which are not translated into proteins. Despite the accumulating evidence on the functional roles of ncRNAs, we are still far from understanding ...
    • Graph walks for classification of histopathological images 

      Olgun, Gülden; Sokmensuer, C.; Gündüz-Demir, Çiğdem (IEEE, 2013)
      This paper reports a new structural approach for automated classification of histopathological tissue images. It has two main contributions: First, unlike previous structural approaches that use a single graph for representing ...
    • Local object patterns for tissue image representation and cancer classification 

      Olgun, Gülden (Bilkent University, 2013)
      Histopathological examination of a tissue is the routine practice for diagnosis and grading of cancer. However, this examination is subjective since it requires visual interpretation of a pathologist, which mainly depends ...
    • miRCoop: identifying cooperating miRNAs via kernel based interaction tests 

      Olgun, Gülden; Tastan, Ö. (IEEE, 2020)
      Although miRNAs can cause widespread changes in expression programs, single miRNAs typically induce mild repression on their targets. Cooperativity among miRNAs is reported as one strategy to overcome this constraint. ...
    • Revisiting the complex architecture of ALS in Turkey: expanding genotypes, shared phenotypes, molecular networks, and a public variant database 

      Tunca, C.; Şeker, T.; Akçimen, F.; Coşkun, C.; Bayraktar, E.; Palvadeau, R.; Zor, S.; Koçoğlu, C.; Kartal, E.; Şen, N. E.; Hamzeiy, H.; Özoğuz-Erimiş, A.; Norman, Utku; Karakahya, Oğuzhan; Olgun, Gülden; Akgün, T.; Durmuş, H.; Şahin, E.; Çakar, A.; Başar-Gürsoy, E.; Babacan-Yıldız, G.; İşak, B.; Uluç, K.; Hanağası, H.; Bilgiç, B.; Turgut, N.; Aysal, F.; Ertaş, M.; Boz, C.; Kotan, D.; İdrisoğlu, H.; Soysal, A.; Uzun-Adatepe, N.; Akalın, M. A.; Koç, F.; Tan, E.; Oflazer, P.; Deymeer, F.; Taştan, Ö.; Çiçek, A. Ercüment; Kavak, E.; Parman, Y.; Başak, A. N. (John Wiley and Sons, 2020)
      The last decade has proven that amyotrophic lateral sclerosis (ALS) is clinically and genetically heterogeneous, and that the genetic component in sporadic cases might be stronger than expected. This study investigates ...