Browsing by Author "Kuru, Halil İbrahim"
Now showing items 1-4 of 4
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DeepSide: a deep learning approach for drug side effect prediction
(IEEE, 2022-01-07)Drug failures due to unforeseen adverse effects at clinical trials pose health risks for the participants and lead to substantial financial losses. Side effect prediction algorithms have the potential to guide the drug ... -
Graph embeddings on protein interaction networks
(Bilkent University, 2019-02)Protein-protein interaction (PPI) networks represent the possible set of interactions among proteins and thereby the genes that code for them. By integrating isolated signals on single genes such as mutations or differential ... -
MatchMaker: A deep learning framework for drug synergy prediction
(IEEE, 2021-06-04)Drug combination therapies have been a viable strategy for the treatment of complex diseases such as cancer due to increased efficacy and reduced side effects. However, experimentally validating all possible combinations ... -
PRER: a patient representation with pairwise relative expression of proteins on biological networks
(Public Library of Science, 2021-05-26)Changes in protein and gene expression levels are often used as features in predictive modeling such as survival prediction. A common strategy to aggregate information contained in individual proteins is to integrate the ...
