Browsing by Author "Kılıç, Gizem"

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A suppressive oligodeoxynucleotide expressing TTAGGG motifs modulates cellular energetics through the mTOR signaling pathway

Yazar, Volkan; Kılıç, Gizem; Bulut, Özlem; Canavar-Yıldırım, Tuğçe; Yağcı, Fuat C.; Gamze, Aykut; Klinman, D. M.; Gürsel, M.; Gürsel, İhsan (Oxford University Press, 2020)

Immune-mediated inflammation must be down-regulated to facilitate tissue remodeling during homeostatic restoration of an inflammatory response. Uncontrolled or over-exuberant immune activation can cause autoimmune diseases, ...
Therapeutic potential of an immunosuppressive oligodeoxynucleotide encapsulated within liposomes on bleomycin-induced mouse model of lung inflammation and fibrosis

Kılıç, Gizem (Bilkent University, 2019-05)

Systemic sclerosis (SSc) is an autoimmune/autoinflammatory disease with unknown etiology. It is characterized by vascular dysfunction, inflammation and disseminated fibrosis of skin or internal organs. Although its prevalence ...