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    • Ketone body signaling mediates intestinal stem cell homeostasis and adaptation to diet 

      Cheng, C.-W.; Biton, M.; Haber, A. L.; Gündüz, Nuray; Eng, G.; Gaynor, L. T.; Tripathi, S.; Çalıbaşı-Koçal, G.; Rickelt, S.; Butty, V. L.; Moreno-Serrano, M.; Iqbal, A. M.; Bauer-Rowe, K. E.; Imada, S.; Ulutaş, M. S.; Mylonas, C.; Whary, M. T.; Levine, S. S.; Başbınar, Y.; Hynes, R. O.; Mino-Kenudson, M.; Deshpande, V.; Boyer, L. A.; Fox, J. G.; Terranova, C.; Rai, K.; Piwnica-Worms, H.; Mihaylova, M. M.; Regev, A.; Yılmaz, Ö. H. (Cell Press, 2019)
      Little is known about how metabolites couple tissue-specific stem cell function with physiology. Here we show that, in the mammalian small intestine, the expression of Hmgcs2 (3-hydroxy-3-methylglutaryl-CoA synthetase 2), ...