Now showing items 1-20 of 134

    • Advances in nanoparticle‐based medical diagnostic and therapeutic techniques 

      Sardan, Melis; Özkan, Alper Devrim; Zengin, Aygül; Tekinay, Ayşe B.; Güler, Mustafa O. (John Wiley & Sons, 2016-03-11)
      Advances in modern medicine have eliminated several major causes of human mortality and considerably extended life expectancies around the world; however, this increase in the global age average has also boosted the ...
    • Alkaline phosphatase-mimicking peptide nanofibers for osteogenic differentiation 

      Gülseren, Gülcihan; Yasa, I. Ceren; Ustahuseyin, Oya; Tekin, E. Deniz; Tekinay, Ayse B.; Güler, Mustafa O. (American Chemical Society, 2015)
      Recognition of molecules and regulation of extracellular matrix synthesis are some of the functions of enzymes in addition to their catalytic activity. While a diverse array of enzyme-like materials have been developed, ...
    • Amphiphilic peptide coated superparamagnetic iron oxide nanoparticles for in vivo MR tumor imaging 

      Ozdemir, A.; Ekiz, M. S.; Dilli, A.; Güler, Mustafa O.; Tekinay, A. B. (Royal Society of Chemistry, 2016)
      Magnetic resonance imaging (MRI) is a noninvasive imaging technique that provides high spatial resolution and depth with pronounced soft-tissue contrast for in vivo imaging. A broad variety of strategies have been employed ...
    • Amyloid inspired self-assembled peptide nanofibers 

      Çınar, Göksu; Ceylan, Hakan; Urel, Mustafa; Erkal, Turan S.; Tekin, E. Deniz; Tekinay, Ayse B.; Dâna, Aykutlu; Güler, Mustafa O. (American Chemical Society, 2012)
      Amyloid peptides are important components in many degenerative diseases as well as in maintaining cellular metabolism. Their unique stable structure provides new insights in developing new materials. Designing bioinspired ...
    • Amyloid-like peptide nanofiber templated titania nanostructures as dye sensitized solar cell anodic materials 

      Acar, H.; Garifullin, R.; Aygun, L. E.; Okyay, Ali Kemal; Güler, Mustafa O. (Royal Society of Chemistry, 2013)
      One-dimensional titania nanostructures can serve as a support for light absorbing molecules and result in an improvement in the short circuit current (Jsc) and open circuit voltage (Voc) as a nanostructured and high-surface-area ...
    • Angiogenic heparin-mimetic peptide nanofiber gel improves regenerative healing of acute wounds 

      Uzunalli, G.; Mammadov R.; Yesildal, F.; Alhan, D.; Ozturk, S.; Ozgurtas, T.; Güler, Mustafa O.; Tekinay, A. B. (American Chemical Society, 2017)
      Wound repair in adult mammals typically ends with the formation of a scar, which prevents full restoration of the function of the healthy tissue, although most of the wounded skin heals. Rapid and functional recovery of ...
    • Angiogenic peptide nanofibers improve wound healing in STZ-induced diabetic rats 

      Senturk, B.; Mercan, S.; Delibasi, T.; Güler, Mustafa O.; Tekinay, A. B. (American Chemical Society, 2016-06)
      Low expressions of angiogenic growth factors delay the healing of diabetic wounds by interfering with the process of blood vessel formation. Heparin mimetic peptide nanofibers can bind to and enhance production and activity ...
    • Angiogenic peptide nanofibers repair cardiac tissue defect after myocardial infarction 

      Rufaihah, A. J.; Yasa, I. C.; Ramanujam, V. S.; Arularasu, S. C.; Kofidis, T.; Güler, Mustafa O.; Tekinay, A. B. (Acta Materialia Inc, 2017)
      Myocardial infarction remains one of the top leading causes of death in the world and the damage sustained in the heart eventually develops into heart failure. Limited conventional treatment options due to the inability ...
    • Antigenic GM3 lactone mimetic molecule integrated mannosylated glycopeptide nanofibers for the activation and maturation of dendritic cells 

      Gunay, Gokhan; Ekiz, Melis Sardan; Ferhati, X.; Richichi, B.; Nativi, C.; Tekinay, Ayse B.; Güler, Mustafa O. (American Chemical Society, 2017)
      The ability of dendritic cells to coordinate innate and adaptive immune responses makes them essential targets for vaccination strategies. Presentation of specific antigens by dendritic cells is required for the activation ...
    • Atomic force microscopy for the investigation of molecular and cellular behavior 

      Ozkan A.D.; Topal, A. E.; Dana, A.; Güler, Mustafa O.; Tekinay, A. B. (Elsevier, 2016-10)
      The present review details the methods used for the measurement of cells and their exudates using atomic force microscopy (AFM) and outlines the general conclusions drawn by the mechanical characterization of biological ...
    • Basal lamina mimetic nanofibrous peptide networks for skeletal myogenesis 

      Yasa, I. C.; Gunduz, N.; Kilinc, M.; Güler, Mustafa O.; Tekinay, A. B. (Nature Publishing Group, 2015)
      Extracellular matrix (ECM) is crucial for the coordination and regulation of cell adhesion, recruitment, differentiation and death. Therefore, equilibrium between cell-cell and cell-matrix interactions and matrix-associated ...
    • Bioactive nanomaterials for neural engineering 

      Sever, Melike; Uyan, İdil; Tekinay, Ayse B.; Güler, Mustafa O. (Springer, Cham, 2016)
      Nervous system is a highly complex interconnected network and higher organisms including humans have limited neural regeneration capacity. Neurodegenerative diseases result in significant cognitive, sensory, or motor ...
    • Bioactive peptide amphiphile nanofibers for cornea regeneration 

      Uzunallı, Gözde; Soran, Zeliha; Dağtaş, Yavuz S.; Aydın, B.; Güler, Mustafa O.; Tekinay, Ayşe B. (John Wiley & Sons, 2012)
    • Bioactive peptide functionalized aligned cyclodextrin nanofibers for neurite outgrowth 

      Hamsici, S.; Cinar, G.; Celebioglu A.; Uyar, Tamer; Tekinay, A. B.; Güler, Mustafa O. (Royal Society of Chemistry, 2017)
      Guidance of neurite extension and establishment of neural connectivity hold great importance for neural tissue regeneration and neural conduit implants. Although bioactive-epitope functionalized synthetic or natural polymeric ...
    • Bioactive self-assembled peptide nanofibers for corneal stroma regeneration 

      Uzunallı, Gözde; Soran, Zeliha Soran; Erkal, Turan S.; Dagdas, Yavuz S; Dinc, E.; Hondur, A. M.; Bilgihan, K.; Aydin B.; Güler, Mustafa O.; Tekinay, Ayşe B. (Elsevier, 2014)
      Defects in the corneal stroma caused by trauma or diseases such as macular corneal dystrophy and keratoconus can be detrimental for vision. Development of therapeutic methods to enhance corneal regeneration is essential ...
    • Bioactive supramolecular peptide nanofibers for regenerative medicine 

      Arslan, Elif; Garip, I. Ceren; Gulseren, Gulcihan; Tekinay, Ayse B.; Güler, Mustafa O. (Wiley, 2014)
      Recent advances in understanding of cell-matrix interactions and the role of the extracellular matrix (ECM) in regulation of cellular behavior have created new perspectives for regenerative medicine. Supramolecular peptide ...
    • Biocompatible electroactive tetra (aniline)-conjugated peptide nanofibers for neural differentiation 

      Arioz, Idil; Erol, Ozlem; Bakan, Gokhan; Dikecoglu, F. Begum; Topal, Ahmet E.; Urel, Mustafa; Dana, Aykutlu; Tekinay, Ayse B.; Güler, Mustafa O. (American Chemical Society, 2018)
      Peripheral nerve injuries cause devastating problems for the quality of patients' lives, and regeneration following damage to the peripheral nervous system is limited depending on the degree of the damage. Use of ...
    • Biocompatible supramolecular catalytic one-dimensional nanofibers for efficient labeling of live cells 

      Khalily, M. A.; Gulseren, G.; Tekinay, A. B.; Güler, Mustafa O. (American Chemical Society, 2015)
      Understanding complex cellular functions requires study and tracking of biomolecules such as proteins, glycans, and lipids in their natural environment. Herein, we report the first supramolecular nanocatalyst for bioorthogonal ...
    • Biosensors for early disease diagnosis 

      Topal, Ahmet E.; Özkan, Alper Devrim; Dana, Aykutlu; Tekinay, Ayse B.; Güler, Mustafa O. (John Wiley & Sons, 2016-03-11)
      This chapter focuses on biosensor types, their detection limits, analysis times, and the diseases they are suitable for detecting. In addition, as nanomaterials are an effective means of producing small‐scale diagnostic ...
    • Bone-like mineral nucleating peptide nanofibers induce differentiation of human mesenchymal stem cells into mature osteoblasts 

      Ceylan, Hakan; Kocabey, Samet; Gulsuner, Hilal Unal; Balcik, O. S.; Güler, Mustafa O.; Tekinay, Ayse B. (American Chemical Society, 2014)
      A bone implant should integrate to the tissue through a bone-like mineralized interface, which requires increased osteoblast activity at the implant-tissue boundary. Modification of the implant surface with synthetic ...