Now showing items 1-4 of 4

    • Angiogenic peptide nanofibers improve wound healing in STZ-induced diabetic rats 

      Senturk, B.; Mercan, S.; Delibasi, T.; Güler, Mustafa O.; Tekinay, A. B. (American Chemical Society, 2016-06)
      Low expressions of angiogenic growth factors delay the healing of diabetic wounds by interfering with the process of blood vessel formation. Heparin mimetic peptide nanofibers can bind to and enhance production and activity ...
    • Diabetic wound regeneration using heparin-mimetic peptide amphiphile gel in db/db mice 

      Senturk, Berna; Demircan, Burak M.; Ozkan, Alper D.; Tohumeken, Sehmus; Delibasi, T.; Güler, Mustafa O.; Tekinay, Ayse B. (Royal Society of Chemistry, 2017)
      There is an urgent need for more efficient treatment of chronic wounds in diabetic patients especially with a high risk of leg amputation. Biomaterials capable of presenting extracellular matrix-mimetic signals may assist ...
    • Improving pancreatic islet in vitro functionality and transplantation efficiency by using heparin mimetic peptide nanofiber gels 

      Uzunalli, Gözde; Tumtas, Yasin; Delibasi, T.; Yasa, Oncay; Mercan, S.; Güler, Mustafa O.; Tekinay, Ayse B. (Elsevier, 2015)
      Pancreatic islet transplantation is a promising treatment for type 1 diabetes. However, viability and functionality of the islets after transplantation are limited due to loss of integrity and destruction of blood vessel ...
    • Virus-like nanostructures for tuning immune response 

      Mammadov R.; Cinar, G.; Gunduz, N.; Goktas, M.; Kayhan, H.; Tohumeken, S.; Topal, A. E.; Orujalipoor, I.; Delibasi, T.; Dana, A.; Ide, S.; Tekinay, A. B.; Güler, Mustafa O. (Nature Publishing Group, 2015)
      Synthetic vaccines utilize viral signatures to trigger immune responses. Although the immune responses raised against the biochemical signatures of viruses are well characterized, the mechanism of how they affect immune ...