Browsing by Author "Ceylan, Hakan"
Now showing items 1-14 of 14
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Amyloid inspired self-assembled peptide nanofibers
(American Chemical Society, 2012)Amyloid peptides are important components in many degenerative diseases as well as in maintaining cellular metabolism. Their unique stable structure provides new insights in developing new materials. Designing bioinspired ... -
Bone-like mineral nucleating peptide nanofibers induce differentiation of human mesenchymal stem cells into mature osteoblasts
(American Chemical Society, 2014)A bone implant should integrate to the tissue through a bone-like mineralized interface, which requires increased osteoblast activity at the implant-tissue boundary. Modification of the implant surface with synthetic ... -
Design, synthesis and characterization of bioinspired nanomaterials for engineering and biomedicine
(Bilkent University, 2014)Nature is an inspirational school for materials scientists. Natural selection process puts a massive pressure on biological organisms giving rise to effective strategies for fabricating materials, which generally outperform ... -
Glycosaminoglycan mimetric peptide nanofibers promote mineralization by osteogenic cells
(Elsevier, 2013)Bone tissue regeneration is accomplished by concerted regulation of protein-based extracellular matrix components, glycosaminoglycans (GAGs) and inductive growth factors. GAGs constitute a significant portion of the ... -
Mechanical properties of self-assembling peptide hydrogels and their effects on cell behaviors
(John Wiley & Sons, 2012) -
Multi-domain short peptide molecules for in situ synthesis and biofunctionalization of gold nanoparticles for integrin-targeted cell uptake
(American Chemical Society, 2015)We describe design and synthesis model of multidomain (modular) peptides (MDPs), which direct a reaction cascade coupling the synthesis and surface functionalization of gold nanoparticles (AuNPs) in a single step. The ... -
Mussel inspired dynamic cross-linking of self-healing peptide nanofiber network
(Wiley, 2013)A general drawback of supramolecular peptide networks is their weak mechanical properties. In order to overcome a similar challenge, mussels have adapted to a pH-dependent iron complexation strategy for adhesion and curing. ... -
Mussel-inspired functionalization of metal surfaces with bioactive self-assembled peptide nanofibers
(John Wiley & Sons, 2012) -
Nanomaterials as tissue adhesives
(John Wiley & Sons, 2016-03-11)Tissue adhesives are used to create functional bonding interfaces between injured tissue parts and between tissues and implanted biomaterials. This chapter provides a critical review of the conventional tissue adhesive ... -
Nanomaterials for bone tissue regeneration and orthopedic implants
(John Wiley & Sons, 2016-03-11)Hierarchical organization and specialized composition of bone extracellular matrix (ECM) control the cellular processes including proliferation, migration, and differentiation for continuous modulation and maintenance of ... -
Selective adhesion and growth of vascular endothelial cells on bioactive peptide nanofiber functionalized stainless steel surface
(Elsevier, 2011)Metal-based scaffolds such as stents are the most preferred treatment methods for coronary artery disease. However, impaired endothelialization on the luminal surface of the stents is a major limitation occasionally leading ... -
Size-controlled conformal nanofabrication of biotemplated three-dimensional TiO2 and ZnO nanonetworks
(Nature, 2013)A solvent-free fabrication of TiO2 and ZnO nanonetworks is demonstrated by using supramolecular nanotemplates with high coating conformity, uniformity, and atomic scale size control. Deposition of TiO2 and ZnO on ... -
Sustained release of ranibizumab from selfasssembled peptide amphiphile microgels
(John Wiley & Sons, 2012)
