Browsing by Author "Brunso-Bechtold, J."
Now showing items 1-3 of 3
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Caloric restriction eliminates the aging-related decline in NMDA and AMPA receptor subunits in the rat hippocampus and induces homeostasis
Shi, L.; Adams, Michelle M.; Linville, M.; Newton, I.; Forbes, M.; Long, A.; Riddle, D.; Brunso-Bechtold, J. (ElsevierAysel Sabuncu Brain Research Center (BAM), 2007)Caloric restriction (CR) extends life span and ameliorates the aging-related decline in hippocampal-dependent cognitive function. In the present study, we compared subunit levels of NMDA and AMPA types of the glutamate ... -
Spatial learning and memory deficits after whole-brain irradiation are associated with changes in nmda receptor subunits in the hippocampus
Shi, L.; Adams, Michelle M.; Long, A.; Carter, C.; Bennett, C.; Sonntag, W.; Nicolle, M.; Robbins, M.; D'Agostino, R.; Brunso-Bechtold, J. (Radiation Research Society., 2006)Whole-brain irradiation is used for the treatment of brain tumors, but can it also induce neural changes, with progressive dementia occurring in 20–50% of long-term survivors. The present study investigated whether 45 Gy ... -
Stability of local brain levels of insulin-like growth factor-I in two well-characterized models of decreased plasma IGF-I
Adams, Michelle M.; Forbes, M; Linville, M.; Riddle, D.; Sonntag, W.; Brunso-Bechtold, J. (Taylor & Francis, 2009)Insulin-like growth factor-I (IGF-I), a functionally important neurotrophic factor, impacts tissues throughout the body including the central nervous system. In addition to the significant proportion of IGF-I that is ...