Now showing items 1-4 of 4

    • Nanoparticle labeling: a new era in vivo tracing the cells in liver studies 

      Akhan, Ece; Aydın, Muammer Merve; İbrahimova, Vusala; Buğdaycı, Kadir Emre; Tuncel, Dönüş; Akçalı, Kamil Can (Elsevier, 2012-04)
      Tracking molecules in vivo has always been challenging and there is increasing demand for tools that allow researchers to trace especially during cell-based therapies. Conjugated polymer based water-dispersible nanoparticles ...
    • Role of FLT3 and its potential interaction partner, Hsp27 in hepatocellular carcinoma 

      Aydın, Muammer Merve; Bayın, N. S.; Akhan, Ece; Can, A.; Akçalı, Kamil Can (Elsevier, 2012-04)
      Regeneration ability of liver is known to be associated with the activation of resident oval cells. Previously our group showed that oval cell marker, FLT3 changes its cellular localization in response to partial hepatectomy ...
    • Role of FLT3 in the proliferation and aggressiveness of hepatocellular carcinoma 

      Aydın, Muammer Merve; Bayın, Nermin Sumru; Acun, T.; Yakıcıer, M. C.; Akçalı, K. C. (TÜBİTAK, 2016)
      Background/aim: Previously we showed that Fms-like tyrosine kinase (FLT3) changes its cellular localization upon partial hepatectomy, suggesting a role in liver regeneration. FLT3 was also shown to play an important function ...
    • Therapeutic approaches to the prevention of liver fibrosis and cancer progression 

      Aydın, Muammer Merve (Bilkent University, 2015-08)
      In our previous studies on liver regeneration, we demonstrated that following partial hepatectomy (PH) FLT3 contributes cellular proliferation that provides a basis for liver regeneration. Moreover, we were able to suggest ...