Browsing by Author "Ariwodola, O. J."
Now showing items 1-3 of 3
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Functional characterization of Des-IGF-1 action at excitatory synapses in the CA1 region of rat hippocampus
Ramsey, M. M.; Adams, Michelle M.; Ariwodola, O. J.; Sonntag, W. E.; Weiner, J. (American Physiological Society, 2005)Insulin-like growth factor-1 (IGF-1) and growth hormone play a major role in the growth and development of tissues throughout the mammalian body. Plasma IGF-1 concentrations peak during puberty and decline with age. We ... -
Growth hormone and insulin-like growth factor-I alter hippocampal excitatory synaptic transmission in young and old rats
Molina, D. P.; Ariwodola, O. J.; Weiner, J. L.; Bechtold, J. K. B.; Adams, Michelle M. (Age Company, 2013)In rats, as in humans, normal aging is characterized by a decline in hippocampal-dependent learning and memory, as well as in glutamatergic function. Both growth hormone (GH) and insulin-like growth factor-I (IGF-I) levels ... -
Growth hormone modulates hippocampal excitatory synaptic transmission and plasticity in old rats
Molina, D. P.; Ariwodola, O. J.; Linville, C.; Sonntag, W. E.; Weiner, J. L.; Brunso-Bechtold, J. K.; Adams, Michelle M. (Elsevier, 2012)Alterations in the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor (AMPA-R) and N-methyl-D-aspartate receptor (NMDA-R) have been documented in aged animals and may contribute to changes in hippocampal-dependent ...