Browsing by Author "Şen, Alper"
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Advances in business analytics at HP laboratories
Beyer, D.; Clearwater, S.; Chen, K. Y.; Feng, Q.; Huberman, B. A.; Jain, S.; Jamal, Z.; Şen, Alper; Tang, H. K.; Tarjan, B.; Ward, J.; Zhang, A.; Zhang, B. (Springer, Boston, 2010)HP Labs’ Business Optimization Lab is a group of researchers focused on developing innovations in business analytics that deliver value to HP. This chapter describes several activities of the Business Optimization Lab, ... -
Codon optimization: A mathematical programing approach
Şen, Alper; Kargar, Kamyar; Akgün, E.; Pınar, Mustafa Ç. (Oxford University Press, 2020-04)Motivation: Synthesizing proteins in heterologous hosts is an important tool in biotechnology. However, the genetic code is degenerate and the codon usage is biased in many organisms. Synonymous codon changes that are ... -
A Conic Integer Programming Approach to Constrained Assortment Optimization under the Mixed Multinomial Logit Model
Şen, Alper; Atamtürk, Alper; Kaminsky, P. (Institute for Operations Research and the Management Sciences (INFORMS), 2017-08-12)We consider the constrained assortment optimization problem under the mixed multinomial logit model. Even moderately sized instances of this problem are challenging to solve directly using standard mixed-integer linear ... -
Delegation of stocking decisions under asymmetric demand information
Alp, Osman; Şen, Alper (Institute for Operations Research and the Management Sciences (INFORMS), 2021-01)Problem definition: We consider the incentive design problem of a retailer that delegates stocking decisions to its store managers who are privately informed about local demand. Academic/practical relevance: Shortages ... -
Financial valuation of supply chain contracts
Pınar, Mustafa Ç.; Şen, Alper; Erön, A. G. (John Wiley & Sons, 2011)This chapter focuses on a single buyer‐single supplier multiple period quantity flexibility contract in which the buyer has options to order additional quantities of goods in case of a higher than expected demand in addition ... -
Lot streaming in multi stage shops
Şen, Alper (Bilkent University, 1994)In this thesis, a number of lot streaming problems in flow, open and job shops are investigated. Lot streaming is the process of splitting a job to allow for overlapping of its operations on various machines resulting ... -
Newsvendor competition under asymmetric cost information
Güler, K.; Körpeoğlu, E.; Şen, Alper (Elsevier B.V., 2018)We study the newsboy duopoly problem under asymmetric cost information. We extend the Lippman and McCardle (1997) of competitive newsboy to the case where the two firms are privately informed about their unit costs. The ... -
A unifying network modeling approach for codon optimization
Karaşan, Oya; Şen, Alper; Tiryaki, Banu; Çiçek, A. Ercüment (Oxford University Press, 2022-06-28)Motivation: Synthesizing genes to be expressed in other organisms is an essential tool in biotechnology. While the many-to-one mapping from codons to amino acids makes the genetic code degenerate, codon usage in a ...