Advisors
Now showing items 1-6 of 6
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Functional characterization of LOC115098:A novel gene conserved in eukaryotic genomes
(Bilkent University, 2007)Loc115098 is a newly identified gene in our laboratory. The gene was firstly discovered in an unrelated study in which the cis-acting regulatory elements of a neighboring gene NIS (Sodium-Iodide Symporter) were investigated. ... -
Functional identification of RASGEF1 family of exchange factors as activators of RAP2, and as interacting partners of CCDC124
(Bilkent University, 2009)Coiled coil domain-124 gene is highly conserved among eukaryotes and the human counterpart encodes a protein with no domain similarities with any previously characterized eukaryotic proteins. In this study, we aimed to ... -
Hanein-1, a novel conserved eukaryotic protein ubiquitously expressed in human tissues
(Bilkent University, 2008)HANEIN-1 was first identified in a study investigating 3’ transcriptional regulatory elements of the Na+ /I- symporter gene. The protein is highly conserved among eukaryotes and bears no domain similarities with any ... -
Identification of novel genetic elements controlling transcriptional regulation of the human Na(formula)/I(formula) symporter (NIS) gene
(Bilkent University, 2006)The function of sodium iodide symporter (NIS) in mammary gland epithelial cells is essential for the accumulation of iodide in mother’s milk, which is the first source of iodide for the synthesis of thyroid hormones in ... -
Monoclonal antibody production for coiled-coil domain containing-124 (CCDC-124) and its molecular characterization
(Bilkent University, 2010)Coiled-coil-domain-containing-124 (CCDC-124) is a novel protein of unknown function. The Ccdc-124 gene is highly conserved among eukaryotic species and is predicted to encode a 223 amino acids long protein. Yeast-two-hybrid ... -
Studies on estradiol dependent transcriptional regulation of human Sodium Iodide Symporter gene in mammary glands
(Bilkent University, 2002)Sodium Iodide Symporter (NIS) is a transmembrane protein, which is expressed in thyroid, mammary gland (mg), stomach, and salivary gland. NIS’s transcriptional regulation in terms of cis-and trans-acting elements in ...
