Advisors
Now showing items 1-3 of 3
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Epigenetic regulation of cancer-testis gene expression
(Bilkent University, 2008)Cancer-testis (CT) genes are composed of mostly X-linked gene families that are widely expressed in cancer, in a coordinate manner, with ideally no expression in normal tissues except spermatogonia, oogonia and trophoblasts. ... -
Mechanisms of SSX gene expression regulation at the promoter level
(Bilkent University, 2009)Cancer Testis (CT) Antigen Genes are not transcribed in any of the adult tissues except spermatogonia, oogonia and trophoblasts. This tight regulation of expression is reversed resulting in the reactivation of CT ... -
An SSX4 knock-in cell line model and in silico analysis of gene expression data as two approaches for investigating mechanisms of cancer
(Bilkent University, 2009)Cancer/testis (CT) genes mapping to the X chromosome (CT-X) are normally expressed in male germ cells but not in adult somatic tissues, with rare exception of oogonia and trophoblast cells; whereas they are aberrantly ...
