Advisors
Now showing items 1-20 of 33
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Cascading logic gates using ion signals generated by photolabile caged compounds
(Bilkent University, 2013)Caged compounds have attracted great attention due to their use in the elucidation of numerous biochemical processes. Photolabile caged compounds release covalently bound moieties upon exposure of ultraviolet light. ... -
Chemical modulation of singlet oxygen generation rates in thermal endoperoxide decomposition & novel fluorescent sensors for hyperphosporylated tau proteins
(Bilkent University, 2016-05)Chemical control over singlet oxygen generation is an open to improvement because of the importance of this reactive species in biological systems. In the first project, we aimed to synthesize a silylated 1,4-dimethylnaphthalene ... -
Chiral Bodipy dyes & photosensitizers for photodynamic therapy and dye-sensitized solar cells
(Bilkent University, 2013)Bodipy is a molecule with many superior properties. After its discovery in 1968, most of the features were not recognized until mid 1990s. Thereafter, many research papers and patents have been produced and the number ... -
Controlled singlet oxygen generation via plasmonic heating of gold nanorods
(Bilkent University, 2015-08)Photodynamic therapy (PDT) is the up-and-coming and developing methodology in order to treat various cancer tissues. The success of therapeutic action is directly related to the presence of cytotoxic singlet oxygen (SO) ... -
Covalent self-assembly of an energy cascade in one step
(Bilkent University, 2015-08)Light harvesting mechanisms include absorption of energy by donor and transfer of the absorbed energy to acceptor. The aim of this process is the channeling of the light at certain wavelength. In this study, energy transfer ... -
Covalently functionalized MSNs as potential photosensitizing agents for PDT
(Bilkent University, 2011)Photodynamic therapy (PDT) is a novel approach for the treatment of some cancers and other non-malignant diseases. PDT aims to kill cancer tissue by the generation of singlet oxygen as a result of excitation of the ... -
Design, synthesis and characterization of activatable photosensitizers for photodynamic therapy
(Bilkent University, 2012)Search for new noninvasive methods for diseases has been significant question for years. Therapeutic properties of light are combined with proper chromophore in order to create fundamentals of photodynamic therapy which ... -
Design, synthesis and characterization of orthogonal bodipy trimers and progress tpwards a singlet oxygen probe
(Bilkent University, 2015-08)Several methods of fighting cancer have been proposed over the years after it was discovered. Photodynamic therapy (PDT) has been part of these methods for many years therefore; too much financial effort has been spent ... -
Fluorescence detection of biological thiols and axially chiral bodipy derivatives and alternative methodologies for singlet oxygen generation for photodynamic action
(Bilkent University, 2014)Calorimetric and luminescent detection of biological thiols namely cysteine (Cys), homocysteine (Hcy) and glutathione (GSH) have attracted great interest due to the their biological significance. There are many reported ... -
A homogeneous system for photogeneration of hydrogen initiated by bodipy based photoinduced electron transfer
(Bilkent University, 2015-08)The key technology to fulfill the energy needs in the future is the generation of fuels by harvesting solar energy. Due to high abundance and low prices of cobalt, water-splitting (based on cobalt) method has received a ... -
Light harvesting and efficient energy transfer in boron dipyrrin dyads and derivatization for potential utility in dye-sensitized solar cells
(Bilkent University, 2008)In bichromophoric supramolecular systems light is harvested by antenna components and excitation energy is channeled into an acceptor component. We have designed and synthesized novel energy transfer cassettes which are ... -
Metal ion release and signaling in molecular logic gate design
(Bilkent University, 2016-10)Mimicking the biological structures is one of the main goals of the natural sciences, because processes are well-organized in nature despite its amazing complexity. On account of this, releasing metal ions at molecular ... -
Molecular logic gates in the activity modulation of potential PDT agents & rational design of selective chloride sensors
(Bilkent University, 2013)Considering the time arrow of science, things are getting smaller and smarter as the information grows immensely. More is known about the molecular and genetic basis of diseases, and therapies become more personalized ... -
Near-IR absorbing Bodipy functionalized Spions : a potential magnetic nanoplatform fo diagnosis and therapy
(Bilkent University, 2012)Photodynamic therapy (PDT), especially with the recent advances in photosensitizer design has already been established as a noninvasive technique for cancer treatment. In PDT, photosensitizers (PSs) are targeted to tumor ... -
Nitroolefin functionalized bodipy dyes for protein labeling
(Bilkent University, 2013)Protein labeling has significant importance in terms of visualizing dynamics of proteins, cell-cell interactions, mechanisms of life cycles of proteins, etc. Proteins are labeled by either synthetic or natural molecules ... -
Non-covalently functionalized SWNTs as potential delivery agents for novel BODIPY*based PDT sensitizers & the design and synthesis of dendritic light harvesters
(Bilkent University, 2009)Photodynamic therapy (PDT) is a non-invasive method used for the treatment of a number of diseases including certain cancers and some cardiovascular diseases. Photodynamic action depends on absorbance of photosensitizer ... -
Novel multichromophoric energy transfer cassettes based on functionalized BODIPY dyes
(Bilkent University, 2012)Energy necessity is one of the leading problems in the world due to the developing technologies and strategies. There are many energy sources, which are being used for years, however; conversion and transfer of the energy ... -
Novel near-ir photosensitizers for photodynamic therapy and designing heavy atom free photosensitizers for the photodynamic therapy
(Bilkent University, 2016-03)Photodynamic therapy (PDT) is a promising and emerging noninvasive treatment modality for the treatment of a great number of malignant and non-malignant diseases. Therapeutic strategy in PDT is performed by combining a ... -
Optimization of orthogonal reactions on bodipy dyes for one-pot synthesis of light harvesting dendrimers
(Bilkent University, 2013)For more than a decade, synthetic organic chemistry has dealt with focusing on highly selective and efficient reactions that can proceed under mild conditions which would then be categorized under the term “orthogonal ... -
Photosensitizers for photodynamic action and synthesis of modules for a molecular demultiplexer
(Bilkent University, 2014)Photodynamic therapy (PDT) is a new therapeutic methodology that uses light as a distinguishing tool for the treatment of diseased cells. In recent years PDT has become one of the most preferred therapies because it is ...
