Advisors
Now showing items 1-12 of 12
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Applications of biomaterials in cancer diagnosis and treatment
(Bilkent University, 2013)Cancer remains to be a major burden of disease worldwide, despite the significant increase in the number of studies that focus on the development of novel diagnostic and treatment strategies. Recently, important part of ... -
Characterization of novel monoclonal antibodies that target proteins differentially expressed in hepatocellular carcinoma : a proteomics approach
(Bilkent University, 2011)Hepatocellular carcinoma (HCC) is the sixth common cancer in the world. Because of the late diagnosis of the disease, survival rates are still poor in the HCC patients. Surveillance strategies have to be developed in ... -
Cloning and expression profile of FLT3 gene during rat liver regeneration
(Bilkent University, 2005)Liver has a unique capacity to regenerate itself upon exposure to viral infections, toxic reactions and cancer formation which result in the loss of hepatocyte. Liver regeneration is a complex phenomenon in which several ... -
Contribution of mesenchymal stem cells in cell based therapies
(Bilkent University, 2010)tem cell research evolved as a new hope and has gained tremendous interest in the last two decades to develop new strategies for many of debilitating diseases. Mesenchymal Stem Cells (MSCs) are multipotent cells capable ... -
Effect of estrogen on apoptotic regulatory mechanisms in mesenchymal stem cell maintenance
(Bilkent University, 2006)Mesenchymal Stem Cells (MSCs) can both self-renew and differentiate into fat, bone, cartilage, and muscle. They have a high therapeutic value due to their differentiation potential and nonimmunogenic characteristics, ... -
The expression of BCL-2 family of genes during liver regeneration
(Bilkent University, 2001)Hepatic regeneration is a process that includes cellular proliferation and cellular death. Apoptosis is the main tool for the organism to control the death in order to prevent the destruction of the tissues, and maintain ... -
Genetic and epigenetic evaluation of the candidate genes in human hepatocellular carcinomas
(Bilkent University, 2010)Hepatocellular carcinoma (HCC) is the fifth most-common cancer and the third most common cause of cancer related mortality worldwide. HCC is also the most common type of liver cancer. Hepatocarcinogenesis is a multistep ... -
Liver regeneration : potential roles of mesenchymal stem cells and toll like receptors
(Bilkent University, 2008)Akçalı -
Role of environmental factors in mesenchymal stem cell biology
(Bilkent University, 2009)Mesenchymal Stem Cells (MSCs) have the abilities of self-renewal and differentiation into fat, bone, cartilage, and muscle tissues. Besides intrinsic mechanisms that control the fate of the MSCs, extrinsic physiological ... -
Role of estrogen on the maintenance and homing capacity of bone marrow derived rat mesenchymal stem cells
(Bilkent University, 2011)Mesenchymal Stem Cells (MSCs) can self renew and differentiate into different cell types like, adipocytes, osteoblasts, chondrocytes, neurons, hepatocytes and endothelial cells. Their ability to differentiate into wide ... -
The role of FLT3 in hepatocellular carcinogenesis
(Bilkent University, 2010)Hepatocellular carcinoma (HCC) is one of the most prevalent cancer types and it has a high mortality rate. Its high incidence is a consequence of lack of biomarkers that could track the progression of the disease. ... -
WNT/(formula)-Catenin signaling pathway activation in epithelial cancers
(Bilkent University, 2006)Wnt signaling is involved in a large set of cellular and developmental processes, and when mis-regulated can lead to both degenerative diseases and many types of cancer. The involvement of Wnt signaling was already well ...
