Advisors
Now showing items 1-8 of 8
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Affinity of glycopeptide nanofibers to growth factors and their effects on cells
(Bilkent University, 2017-09)The development of scaffolds for growth factor delivery is a promising approach for tissue regeneration applications due to their crucial roles during regeneration. Growth factor secretion and interactions with glycosaminoglycans ... -
Age and gender alter synaptic proteins in zebrafish (Danio Rerio) models of normal and delayed aging
(Bilkent University, 2017-07)Cognitive decline occurs during normal aging in some specific domains of cognitive abilities including but not limited to episodic memory, divided attention and executive functions, however, it is not a unitary decline ... -
Age related alterations of adult neurogenesis and astrocytes in Zebrafish (Danio Rerio)
(Bilkent University, 2019-09)Brain aging is marked by a decline in cognitive abilities and associated with neurodegenerative disorders. In order to identify appropriate interventions to change the course of brain aging and age-related neurological ... -
Alterations in the molecular properties of neural stem cells from aged brains and brain tumors
(Bilkent University, 2017-07)It is known that new neuron formation in the brain continues throughout the life of an organism. In the adult human brain, it was proven that neurogenesis in the hippocampus is higher than expected, almost 700 new neurons ... -
Analysis of movement disorder-related genes following knockdowns of ANO10, WDR81, and VLDLR in zebrafish (DANIO RERIO)
(Bilkent University, 2018-07)Movement Disorders are the neurological symptoms that cause alterations in normal motility, posture and muscle tone. Certain brain areas, such as the cerebellum, mediate correct motor control and functioning. When defects ... -
Effects of aging and short-term dietary restriction on neurogenesis and cellular senescence in the zebrafish (Danio Reio) brain
(Bilkent University, 2016-09)Currently we know from rodent and fish studies that adult neuron generation is reduced but still continues in old animals with a dynamic change throughout aging. This process occurs mainly in hippocampal region, which is ... -
Expression of key synaptic proteins in Zebrafish (Danio Rerio) brain following caloric restriction and its mimetic and their relationship with gender
(Bilkent University, 2017-01)Aging is a progressive decline of physiological functioning and metabolic processes. Among all the organs, the brain seems to be the most vulnerable part of the body to the age-related changes because of the relatively ... -
Investigating the mechanisms of telomere maintenance in zebrafish tissues and human brain cancer cell lines
(Bilkent University, 2019-09)Telomeres are nucleoprotein complexes formed at each end of the chromosomes to protect these ends from deterioration. In each round of cellular division, telomeric sequences shorten due to the end replication problem of ...
