Now showing items 41-60 of 64

    • Naringenin inhibits neointimal hyperplasia following arterial reconstruction with interpositional vein graft 

      Cayci, C.; Wahlquist, T. C.; Seckin, S. I.; Ozcan, V.; Tekinay, A. B.; Martens, T. P.; Oz, M. C.; Ascherman, J. A. (Lippincott Williams & Wilkins, 2010)
      Vessels respond to injury by a healing process that includes the development of neointima. Stenosis secondary to neointima formation is the main cause of failure following arterial reconstructions. Vessel wall homeostasis ...
    • Non-intercalative, deoxyribose binding of boric acid to calf thymus DNA 

      Ozdemir, A.; Gursacli, R. T.; Tekinay, T. (Springer, 2014)
      The present study characterizes the effects of the boric acid binding on calf thymus DNA (ct-DNA) by spectroscopic and calorimetric methods. UV-Vis absorbance spectroscopy, circular dichroism (CD) spectroscopy, transmission ...
    • Odour intensity learning in fruit flies 

      Yarali, A.; Ehser, S.; Hapil F.Z.; Huang J.; Gerber, B. (2009)
      Animals' behaviour towards odours depends on both odour quality and odour intensity. While neuronal coding of odour quality is fairly well studied, how odour intensity is treated by olfactory systems is less clear. Here ...
    • One-Step Fabrication of Biocompatible Multifaceted Nanocomposite Gels and Nanolayers 

      Topuz, F.; Bartneck, M.; Pan, Y.; Tacke, F. (American Chemical Society, 2017)
      Nanocomposite gels are a fascinating class of polymeric materials with an integrative assembly of organic molecules and organic/inorganic nanoparticles, offering a unique hybrid network with synergistic properties. The ...
    • Parasite stress and pathogen avoidance relate to distinct dimensions of political ideology across 30 nations 

      Tybur J.M.; Inbar Y.; Aarøe L.; Barclay P.; Barlowe F.K.; De Barra M.; Beckerh D.V.; Borovoi L.; Choi I.; Choik J.A.; Consedine N.S.; Conway A.; Conway J.R.; Conway P.; Adoric V.C.; Demirci D.E.; Fernández A.M.; Ferreirat D.C.S.; Ishii K.; Jakšic I.; Ji T.; Van Leeuwen F.; Lewis D.M.G.; Li N.P.; McIntyre J.C.; Mukherjee S.; Park J.H.; Pawlowski B.; Petersen M.B.; Pizarro D.; Prodromitis G.; Prokop P.; Rantala M.J.; Reynolds L.M.; Sandin B.; Sevi, Barış; De Smet D.; Srinivasan N.; Tewari S.; Wilson C.; Yong J.C.; Žezelj I. (National Academy of Sciences, 2016)
      People who are more avoidant of pathogens are more politically conservative, as are nations with greater parasite stress. In the current research, we test two prominent hypotheses that have been proposed as explanations ...
    • Patrolling monocytes control tumor metastasis to the lung 

      Hanna, R. N.; Cekic, C.; Sag, D.; Tacke, R.; Thomas, G. D.; Nowyhed, H.; Herrley, E.; Rasquinha, N.; McArdle, S.; Wu, R.; Peluso, E.; Metzger, D.; Ichinose, H.; Shaked, I.; Chodaczek, G.; Biswas, S. K.; Hedrick, C. C. (American Association for the Advancement of Science, 2015)
      The immune system plays an important role in regulating tumor growth and metastasis. Classical monocytes promote tumorigenesis and cancer metastasis, but how nonclassical "patrolling" monocytes (PMo) interact with tumors ...
    • Phased-array MRI of canine prostate using endorectal and endourethral coils 

      Yung, A. C.; Oner, A. Y.; Serfaty, J-M.; Feneley, M.; Yang, X.; Atalar, Ergin (John Wiley & Sons, Inc., 2003)
      A four-channel phased array consisting of one surface coil, two endorectal coils, and one flexible endourethral loop coil was designed for MRI of the canine prostate. The endorectal coils provide high signal in the posterior ...
    • Prostate stem cell antigen is an endogenous lynx1-like prototoxin that antagonizes α7-containing nicotinic receptors and prevents programmed cell death of parasympathetic neurons 

      Hruska, M.; Keefe J.; Wert, D.; Tekinay, A.B.; Hulce J.J.; Ibañez-Tallon I.; Nishi, R. (2009)
      Vertebrate α-bungarotoxin-like molecules of the Ly-6 superfamily have been implicated as balancers of activity and survival in the adult nervous system. To determine whether a member of this family could be involved in the ...
    • The prosurvival IKK-related kinase IKKϵ integrates LPS and IL17A signaling cascades to promote Wnt-dependent tumor development in the intestine 

      Göktuna, S. I.; Shostak, K.; Chau, T.-L.; Heukamp, L.C.; Hennuy, B.; Duong, H.-Q.; Ladang, A.; Close, P.; Klevernic, I.; Olivier, F.; Florin, A.; Ehx, G.; Baron, F.; Vandereyken, M.; Rahmouni, S.; Vereecke, L.; Loo, G. V.; Büttner, R.; Greten, F. R.; Chariot, A. (American Association for Cancer Research, 2016-05)
      Constitutive Wnt signaling promotes intestinal cell proliferation, but signals from the tumor microenvironment are also required to support cancer development. The role that signaling proteins play to establish a tumor ...
    • Protein-releasing conductive anodized alumina membranes for nerve-interface materials 

      Altuntas, S.; Buyukserin, F.; Haider, A.; Altinok, B.; Bıyıklı, Necmi; Aslim, B. (Elsevier Ltd, 2016)
      Nanoporous anodized alumina membranes (AAMs) have numerous biomedical applications spanning from biosensors to controlled drug delivery and implant coatings. Although the use of AAM as an alternative bone implant surface ...
    • Purinergic regulation of the immune system 

      Cekic, C.; Linden, J. (Nature Publishing Group, 2016)
      Cellular stress or apoptosis triggers the release of ATP, ADP and other nucleotides into the extracellular space. Extracellular nucleotides function as autocrine and paracrine signalling molecules by activating cell-surface ...
    • Regulation of Homer and group I metabotropic glutamate receptors by nicotine 

      Kane, J. K.; Hwang, Y.; Konu, O.; Loughlin, S. E.; Leslie, F. M.; Li, M. D. (Wiley-Blackwell Publishing Ltd., 2005)
      The present study focuses on the nicotine-induced modulation of mRNA and protein expression of a number of genes involved in glutamatergic synaptic transmission in rat brain over different time periods of exposure. A ...
    • A role for LYNX2 in anxiety-related behavior 

      Tekinay, A.B.; Nong, Y.; Miwa J.M.; Lieberam I.; Ibanez-Tallon I.; Greengard P.; Heintz, N. (2009)
      Anxiety disorders are the most prevalent mental disorders in developed societies. Although roles for the prefrontal cortex, amygdala, hippocampus and mediodorsal thalamus in anxiety disorders are well documented, molecular ...
    • A simple analytical expression for the gradient induced potential on active implants during MRI 

      Turk, E.A.; Kopanoglu, E.; Guney, S.; Bugdayci, K.E.; Ider, Y. Z.; Erturk, V. B.; Atalar, Ergin (2012)
      During magnetic resonance imaging, there is an interaction between the time-varying magnetic fields and the active implantable medical devices (AIMD). In this study, in order to express the nature of this interaction, ...
    • SOX1 antibodies are markers of paraneoplastic Lambert-Eaton myasthenic syndrome 

      Sabater, L.; Titulaer, M.; Saiz, A.; Verschuuren, J.; Güre, A. O.; Graus, F. (Lippincott Williams & Wilkins, 2008)
      BACKGROUND/OBJECTIVE: We reported that 43% of patients with Lambert-Eaton myasthenic syndrome (LEMS) and small cell lung cancer (SCLC) had an antibody called anti-glial nuclear antibody (AGNA), defined by the immunoreaction ...
    • Spatial organization of functional groups on bioactive supramolecular glycopeptide nanofibers for differentiation of mesenchymal stem cells (MSCs) to brown adipogenesis 

      Caliskan, O. S.; Sardan, Ekiz M.; Tekinay, A. B.; Güler, Mustafa O. (American Chemical Society, 2016-12)
      Spatial organization of bioactive moieties in biological materials has significant impact on the function and efficiency of these systems. Here, we demonstrate the effect of spatial organization of functional groups including ...
    • Strain-and region-specific gene expression profiles in mouse brain in response to chronic nicotine treatment 

      Wang, J.; Gutala, R.; Hwang, Y. Y.; Kim J. -M.; Konu, O.; Ma, J. Z.; Li, M. D. (Wiley-Blackwell Publishing, 2008)
      A pathway-focused complementary DNA microarray and gene ontology analysis were used to investigate gene expression profiles in the amygdala, hippocampus, nucleus accumbens, prefrontal cortex (PFC) and ventral tegmental ...
    • Surface-modified bacterial nanofibrillar PHB scaffolds for bladder tissue repair 

      Karahaliloǧlu, Z.; Demirbilek, M.; Şam, M.; Saǧlam, N.; Mizrak, A. K.; Denkbaş, E. B. (Taylor and Francis Ltd., 2016)
      The aim of the study is in vitro investigation of the feasibility of surface-modified bacterial nanofibrous poly [(R)-3-hydroxybutyrate] (PHB) graft for bladder reconstruction. In this study, the surface of electrospun ...
    • System for MR image-guided prostate interventions: Canine study 

      Susil, R. C.; Krieger, A.; Derbyshire, J. A.; Tanacs, A.; Whitcomb, L. L.; Fichtinger, G.; Atalar, Ergin (Radiological Society of North America, Inc.Radiological Society of North America, Inc., 2003)
      The purpose of this study was to demonstrate the use of a transrectal system that enables precise magnetic resonance (MR) image guidance and monitoring of prostate interventions. The system used a closed-bore 1.5-T MR ...
    • Systematic discovery of Rab GTPases with synaptic functions in Drosophila 

      Chan, C.-C.; Scoggin, S.; Wang, D.; Cherry, S.; Dembo, T.; Greenberg, B.; Jin, E.J.; Kuey, C.; Lopez, A.; Mehta, S.Q.; Perkins, T.J.; Brankatschk, M.; Rothenfluh, A.; Buszczak, M.; Hiesinger P.R. (2011)
      Background: Neurons require highly specialized intracellular membrane trafficking, especially at synapses. Rab GTPases are considered master regulators of membrane trafficking in all cells, and only very few Rabs have known ...