Ustahüseyin, Oya2016-01-082016-01-082013http://hdl.handle.net/11693/15545Ankara : Materials Science and Nanotechnology Program of Graduate School of Engineering and Science of Bilkent University, 2013.Thesis (Master's) -- Bilkent University, 2013.Includes bibliographical references leaves 116-125.Organic-inorganic hybrid structures play a number of distinguished roles in the living milieu. For instance, metal ions function as cofactors of enzymes and apatite mineralization in bone is driven by collagen nanofibers serve as both physical and chemical templates. These unique interactions in natural systems are examples for development of synthetic materials for many applications such as catalysts, artificial enzymes or materials for regenerative medicine etc. Manufacturing a catalyst at the nanoscale is important due to increased specific surface area and reduced diffusion path length. In this thesis, we demonstrated peptide based bioinspired nanomaterials. The self-assembled peptide nanofibers were utilized as templates for palladium nanoparticle formation. Functionalization of insoluble electrospun nanofibers with a heavy metal binding peptide sequence was utilized to remove toxic metal ions from water. In addition, peptide amphiphile nanofibers complexed with ZnII were used as enzyme mimics. The resulting nanostructures resemble natural bone alkaline phosphatase activity, which is a major enzyme for natural bone apatite formation.xxiii, 215 leaves, graphics, illustrationsEnglishinfo:eu-repo/semantics/openAccessPeptide amphiphileself-assemblynanofiberspalladium catalysiswater cleaningapatite formationartificial metalloenzymeQP552.P4 U78 2013Peptides--Synthesis.Nanostructures.Solid-phase synthesis.Nanostructured materials.Thesis