Çetin, BarbarosTaze, SerdarAsik, M.D.Tuncel, S.A.2016-02-082016-02-0820130888-8116http://hdl.handle.net/11693/27930Conference name: Proceedings of the ASME 2013 Fluids Engineering Division Summer Meeting FEDSM2013Date of Conference: July 7–11 2013Chitosan nanoparticles have a biodegradable, biocompatible, non-toxic structure, and commonly used for drug delivery systems. In this paper, simulation of a microfluidic device for the synthesis of chitosan nanoparticle is presented. The flow filed together with the concentration field within the microchannel network is simulated using COMSOL Multiphysics® simulation environment. Different microchannel geometries are analyzed, and the mixing performance of these configurations are compared. As a result, a 3D design for a microfluidics platform which includes four channel each of which performs the synthesis in parallel is proposed. Future research directions regarding the fabrication of the microfluidic device and experimentation phase are addressed and discussed. Copyright © 2013 by ASME.EnglishChitosan nanoparticlesConcentration fieldsDrug delivery systemFuture research directionsMicro-fluidic devicesMicrochannel geometriesMicrochannel networkSimulation environmentBiocompatibilityDrug deliveryFluidic devicesMicrofluidicsMultiphase flowNanoparticlesChitosanConference Paper10.1115/FEDSM2013-16349