Yağcı, Fuat CemGüçlüler, GözdeKıran, F.Gürsel, İhsan2019-07-082019-07-082012-05http://hdl.handle.net/11693/52144Conference Name: 10th CIMT Annual Meeting, Towards Next-Generation Cancer Immunotherapy, 2012Date of Conference: 23-25 May 2012Synthetic oligodeoxynucleotides (CpG-ODNs) and bacterial DNA containing unmethylated CpG dinucleotides (CpG motifs) are clinical candidates as anti-cancer agents, immune adjuvants, anti-allergens, and stand alone immunoprotective agents. Two different classes of CpG-ODNs were identified for clinical applications. B-Class ODNs, also known as K-type CpG ODN, have phosphorothioate backbones and potent B- cell activators. A-Class ODNs (or D-type ODNs) have mixed backbone and flanking G-runs at their 3`and 5-ends.EnglishConference Paper