Ceylan, Hakan2016-01-082016-01-082014http://hdl.handle.net/11693/17088Ankara : The Materials Science and Nanotechnology Program and the Graduate School of Engineering and Science of Bilkent University, 2014.Thesis (Ph. D.) -- Bilkent University, 2014.Includes bibliographical references leaves 227-247.Nature is an inspirational school for materials scientists. Natural selection process puts a massive pressure on biological organisms giving rise to effective strategies for fabricating materials, which generally outperform their man-made counterparts. Mimicking physical and chemical features of biological materials can greatly aid in overcoming existing design constraints of engineering and medicine. In this dissertation, a reductionist, bottom-up approach is demonstrated to recapitulate biological functionalities in fully-synthetic hybrid constructs. For material design, the potential of short, rationally-designed peptides for programmed organization into nanostructured materials is explored. The resulting nano-ordered materials exhibit multifunctional and adaptive properties, which can be tailored by the information within monomeric peptide sequences as well as the emerging properties upon their self-assembly. In light of these, design, synthesis and characterization of the prototypes of nanostructured functional materials are described in the context of regenerative medicine and biomineralization.xix, 248 leaves, charts, illustrationsEnglishinfo:eu-repo/semantics/openAccessBioinspired MaterialsFunctional Self-AssemblyBiomaterialsSurface FunctionalizationBiomineralizationQT36.5 .C49 2014Biomedical materials.Nanostructured materials.Biomineralization.Thesis