Ahsen, M. E.Özbay, HitayNiculescu, S. -I.2016-02-082016-02-0820151474-6670http://hdl.handle.net/11693/27885Date of Conference: 28–30 June 2015Conference Name: 12th IFAC Workshop on Time Delay Systems, TDS 2015A stability condition is derived for cyclic systems with time delayed negative feedback. The result is an extension of the so-called secant condition, which is originally developed for systems without time delays. This extension of the secant condition gives a new local stability condition for a model of GRNs (Gene Regulatory Networks) under negative feedback. Stability robustness of homogenous networks is also investigated.EnglishGene regulatory networksLocal stabilitySecant conditionTime delayDelay control systemsConference Paper10.1016/j.ifacol.2015.09.372