Buyukdagli, S.Blossey, R.Ala-Nissila, T.2016-02-082016-02-0820150031-9007http://hdl.handle.net/11693/22414We predict streaming current inversion with multivalent counterions in hydrodynamically driven polymer translocation events from a correlation-corrected charge transport theory including charge fluctuations around mean-field electrostatics. In the presence of multivalent counterions, electrostatic many-body effects result in the reversal of the DNA charge. The attraction of anions to the charge-inverted DNA molecule reverses the sign of the ionic current through the pore. Our theory allows for a comprehensive understanding of the complex features of the resulting streaming currents. The underlying mechanism is an efficient way to detect DNA charge reversal in pressure-driven translocation experiments with multivalent cations. © 2015 American Physical Society.EnglishElectrostaticsIonsPolymersStatistical mechanicsCharge fluctuationsCharge reversalMany-body effectMultivalent cationsMultivalent counterionsPolymer translocationPressure-drivenStreaming currentDNAcationDNAelectrolytechemical modelchemistryhydrodynamicsnanoporestatic electricityCationsDNAElectrolytesHydrodynamicsModels, ChemicalNanoporesStatic ElectricityArticle10.1103/PhysRevLett.114.088303