Bayram, C.Mizrak, A.K.Aktürk, S.Kurşaklioǧlu H.Iyisoy, A.Ifran, A.Denkbaş, E.B.2016-02-082016-02-08201017486041http://hdl.handle.net/11693/22464316L-type stainless steel is a raw material mostly used for manufacturing metallic coronary stents. The purpose of this study was to examine the chemical, wettability, cytotoxic and haemocompatibility properties of 316L stainless steel stents which were modified by plasma polymerization. Six different polymeric compounds, polyethylene glycol, 2-hydroxyethyl methacrylate, ethylenediamine, acrylic acid, hexamethyldisilane and hexamethyldisiloxane, were used in a radio frequency glow discharge plasma polymerization system. As a model antiproliferative drug, mitomycin-C was chosen for covalent coupling onto the stent surface. Modified SS 316L stents were characterized by water contact angle measurements (goniometer) and x-ray photoelectron spectroscopy. C1s binding energies showed a good correlation with the literature. Haemocompatibility tests of coated SS 316L stents showed significant latency (t-test, p < 0.05) with respect to SS 316L and control groups in each test. © 2010 IOP Publishing Ltd.EnglishAngle measurementBinding energyBiocompatibilityCarboxylic acidsContact angleCorrosion resistant alloysGlow dischargesOrganic acidsPlasma polymerizationPolyethylene glycolsPolyethylene oxidesPolyethylenesPolymersX ray photoelectron spectroscopy2-hydroxyethyl methacrylate316 L stainless steelAcrylic acidsAnti-proliferativeControl groupsCoronary stentsCovalent couplingsCytotoxicEthylene diamineGood correlationsHaemocompatibilityHexamethyl disiloxaneHexamethyldisilanesIn-vitroIntra-coronary stentsMitomycin CPolymeric compoundsPolymerization systemsRadio frequency glow dischargeSurface-modifiedWater contact angle measurementStainless steel2 hydroxyethyl methacrylateacrylic acidethylenediaminehexamethyldisilanehexamethyldisiloxanemacrogolmitomycin Csilane derivativestainless steelunclassified drug2 hydroxyethyl methacrylateantineoplastic antibioticbiomaterialmacrogol derivativemethacrylic acid derivativemitomycinpolymeranimal cellarticlebiocompatibilitycontact anglecontrolled studycoronary stentcytotoxicityhumanmousenonhumanphysical chemistryplasmapolymerizationsurface propertywettabilitybloodblood clotting testbody fluidchemistrycomparative studystenttoxicity testingX ray photoelectron spectroscopyAntibiotics, AntineoplasticBloodBlood Coagulation TestsBody FluidsCoated Materials, BiocompatibleHumansMethacrylatesMitomycinPhotoelectron SpectroscopyPolyethylene GlycolsPolymersStainless SteelStentsSurface PropertiesToxicity TestsWettabilityArticle10.1088/1748-6041/5/5/055007