Kim, Jeremie S.Firtina, CanCavlak, Meryem BanuÇalı, Damla ŞenolHajinazar, NastaranAlser, MohammedAlkan, CanMutlu, Onur2025-02-182025-02-182024-08-191545-5963https://hdl.handle.net/11693/116390AirLift is the first read remapping tool that enables users to quickly and comprehensively map a read set, that had been previously mapped to one reference genome, to another similar reference. Users can then quickly run a downstream analysis of read sets for each latest reference release. Compared to the state-of-the-art method for remapping reads (i.e., full mapping), AirLift reduces the overall execution time to remap read sets between two reference genome versions by up to 27.4×. We validate our remapping results with GATK and find that AirLift provides high accuracy in identifying ground truth SNP/INDEL variantsEnglishCC BY 4.0 (Attribution 4.0 International Deed)https://creativecommons.org/licenses/by/4.0/BioinformaticsRemappingRead mappingLiftoverArticle10.1109/TCBB.2024.34333781557-9964