Munir, BadarYağcı, Bilge BanuZorlu, YunusTürkmen, Yunus Emre2025-02-232025-02-232024-07-100022-3263https://hdl.handle.net/11693/116708We developed an efficient method that enables selective photodimerization of 5-arylpenta-2,4-dienoic acids (i.e., vinylogous cinnamic acids). The use of 1,8-dihydroxynaphthalene as a template ensures proximity of the two reacting olefins so that irradiation of template-bound dienoic acids gives mono [2 + 2] cycloaddition products in good to excellent yields (up to 99%), as single regioisomers, and with high diastereoselectivities (dr = 3:1 to 13:1). The geometrical and stereochemical features of compounds 12a, 16a, and 22a were analyzed by X-ray crystallography.EnglishCC BY 4.0 (Attribution 4.0 International Deed)https://creativecommons.org/licenses/by/4.0/Solid-stateMetal-complexConstructionActivationCrystalsArticle10.1021/acs.joc.4c013741520-6904