Gezici, Ö.Durmaz, I.Güven, E. B.Ünal, Ö.Özgün, A.Cetin Atalay, R.Tuncel, D.2016-02-082016-02-0820142046-2069http://hdl.handle.net/11693/26633Multifunctional nanoparticles based on a green emitting, hydrophobic conjugated polymer, poly[(9,9-bis{propeny}fluorenyl-2,7-diyl)-co-(1,4-benzo-{2,1,3}-thiodiazole)] (PPFBT), that acts both as a fluorescent reporter and a matrix to accommodate an anti-cancer compound, camptothecin (CPT), were prepared, characterized and their potential as a fluorescent probe for cell imaging and as a drug delivery vehicle were evaluated via in vitro cell assays. The cell viability of human hepatocellular carcinoma cell line (Huh7) was investigated in the absence and presence of CPT with sulforhodamine B (SRB) and real-time cell electronic sensing (RT-CES) cytotoxicity assays.EnglishCamptothecin (CPT)Cytotoxicity assaysDrug delivery vehiclesFluorescent reporterHepatocellular carcinoma cellMulti-functional nanoparticlesPolymer nanoparticlesReal-time cell electronic sensingDrug deliveryCell cultureArticle10.1039/c3ra45120h