Cardone, M. F.D'Addabbo, P.Alkan C.Bergamini, C.Catacchio, C. R.Anaclerio, F.Chiatante, G.Marra, A.Giannuzzi, G.Perniola, R.Ventura M.Antonacci, D.2018-04-122018-04-1220160960-7412http://hdl.handle.net/11693/37397Grapevine (Vitis vinifera L.) is one of the world's most important crop plants, which is of large economic value for fruit and wine production. There is much interest in identifying genomic variations and their functional effects on inter-varietal, phenotypic differences. Using an approach developed for the analysis of human and mammalian genomes, which combines high-throughput sequencing, array comparative genomic hybridization, fluorescent in�situ hybridization and quantitative PCR, we created an inter-varietal atlas of structural variations and single nucleotide variants (SNVs) for the grapevine genome analyzing four economically and genetically relevant table grapevine varieties. We found 4.8 million SNVs and detected 8% of the grapevine genome to be affected by genomic variations. We identified more than 700 copy number variation (CNV) regions and more than 2000 genes subjected to CNV as potential candidates for phenotypic differences between varietiesEnglishPlantFluorescenceCandidate genesCopy number variationGenomic variationHigh-throughput sequencingSingle nucleotide polymorphismSRP009057Table grapeVitis vinifera L.BreweriesChromosomesCropsMammalsNucleotidesPolymerase chain reactionThroughputCandidate genesCopy number variationsGenomic variationHigh-throughput sequencingSingle nucleotide polymorphismsTable grapesVitis vinifera lGenesComparative genomic hybridizationCopy number variationFluorescence in situ hybridizationGeneticsPlant genomePolymerase chain reactionProceduresVitisComparative genomic hybridizationDNA copy number variationsGenomeIn situ hybridizationPolymerase chain reactionVitisArticle10.1111/tpj.13274