Browsing by Subject "Conventional methods"
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Item Open Access Advances in plasmonic technologies for point of care applications(American Chemical Society, 2014) Tokel, Onur; İnci, Fatih; Demirci, UtkanInfectious diseases have considerable economic and societal impact on developing settings. For instance, malaria is observed more commonly in sub-Saharan Africa and India. The societal impact of acquired immune deficiency syndrome (AIDS) and tuberculosis is high, through targeting adults in villages and leaving behind declining populations. Highly sensitive and specific lab assays such as cell culture methods, polymerase chain reaction (PCR), and enzyme-linked immunosorbent assay (ELISA) are available for diagnosis of infectious diseases in the developed world. They require sample transportation, manual preparation steps, and skilled and well-trained technicians. These clinical conventional methods provide results in several hours to days, precluding rapid detection and response at the primary care settings. Another diagnostic challenge is identifying multiple pathogens.Item Open Access Carcinoma cell line discrimination in microscopic images using unbalanced wavelets(IEEE, 2012-03) Keskin, Furkan; Suhre, Alexander; Erşahin, Tüli,; Çetin Atalay, Rengül; Çetin, A. EnisCancer cell lines are widely used for research purposes in laboratories all over the world. In this paper, we present a novel method for cancer cell line image classification, which is very costly by conventional methods. The aim is to automatically classify 14 different classes of cell lines including 7 classes of breast and 7 classes of liver cancer cells. Microscopic images containing irregular carcinoma cell patterns are represented by randomly selected subwindows which possibly correspond to foreground pixels. For each subwindow, a correlation descriptor utilizing the fractional unbalanced wavelet transform coefficients and several morphological attributes as pixel features is computed. Directionally selective textural features are preferred primarily because of their ability to characterize singularities at multiple orientations, which often arise in carcinoma cell lines. A Support Vector Machine (SVM) classifier with Radial Basis Function (RBF) kernel is employed for final classification. Over a dataset of 280 images, we achieved an accuracy of 88.2%, which outperforms the classical correlation based methods. © 2012 IEEE.Item Open Access Chromium(VI) biosorption and bioaccumulation by Live and acid-modified biomass of a novel morganella morganii isolate(Taylor and Francis, 2014) Ergul-Ulger, Z.; Ozkan A.D.; Tunca E.; Atasagun, S.; Tekinay, T.Conventional methods of chromium removal are often insufficient for the remediation of chromium-contaminated natural environments, necessitating the development of alternative strategies. In this paper, we report the isolation of a novel Morganella morganii strain capable of reducing hexavalent chromium to its less-toxic and less-soluble trivalent form. Cr(VI) reduction by this strain was evaluated in both acidic environments and conditions reflecting natural freshwater sources. The isolate achieved equilibrium within 3 h and displayed a specific uptake rate of 24.30 ± 1.67 mg Cr(VI)/g biomass following HCl treatment. Without acid treatment, a reduction of over 90% was recorded within 72 h for an initial Cr(VI) concentration 20 mg/L, corresponding to a Cr(VI) removal capacity of 19.36 ± 1.89 mg/g. Absorption data of acid-treated STB5 biomass most closely followed the Toth and Langmuir models. FTIR results indicate that hydroxyl groups and extracellular or cell membrane polysaccharides may be potential adsorption sites for hexavalent chromium. Our results suggest that the isolate may be used in situ for treatment of polluted freshwater environments. Copyright © Taylor & Francis Group, LLC.Item Open Access Effect of the off-focus shift of the feed on the radiation characteristics of a 2-D parabolic reflector antenna(IEEE, 2010) Oğuzer, T.; Altıntaş, A.; Nosich, AlexanderThe parabolic reflector antennas are widely used in the telecommunication systems and generally have large aperture sizes like 50λ to 80λ and larger. Their reliable full-wave analysis with the conventional Method of Moments (MoM) or with the other numerical methods is difficult because of inaccessible speed and accuracy. This statement is valid both for 3D and 2D reflector antennas in both polarizations. The Method of Analytical Regularization (MAR) constitutes an alternative solution compared to the ordinary MoM, which can provide only 1-2 digit accuracy. It provides finer accuracy within a reasonable computation time because the computational error can be decreased simply by increasing the matrix size in MAR. We have previously developed this method for the accurate simulation of the arbitrary conical section profile 2D reflector antennas, and the corresponding codes have provided us with accurate benchmark data. Here we study a similar problem however with the feed simulated by Complex Source Point (CSP) source located at an off-focus point on the symmetry axis of a front-fed reflector antenna. The numerical results are presented for the radiation characteristics including the forward and backward directivities and the radiation patterns in all directions. © 2010 IEEE.Item Open Access Method to enlarge the hologram viewing window using a mirror module(2009) Kang H.; Ohmura, N.; Yamaguchi, T.; Yoshikawa H.; Kim, S.-C.; Kim, E.-S.A liquid crystal panel for a video projector is often used for holographic television. However, its pixel size and pixel number are not enough for practical holographic 3-D display. Therefore, a multipanel configuration is generally used to increase the viewing window and displayed image size, and many spatial light modulators should be used in them. We propose a novel method to increase the viewing window of a holographic display system. The proposed method, which is implemented by using a mirror module and 4-f lens set, is to reconfigure the beam shape reflected by a spatial light modulator. The equipment is applied to a holographic display system, which has only a single spatial light modulator; a hologram could be displayed in a wider viewing window by the equipment than that of the conventional method. By the proposed method, the resolution of the reconfigured spatial light modulator has double resolution in the horizontal direction. Inversely, the vertical resolution is decreased. Even if the vertical resolution is decreased, a viewer could get 3-D effect because humans get more 3-D information in the horizontal direction. We have experimented using a liquid crystal on silicon (LcOS), whose resolution is 4096×2160pixels. The reconfigured resolution by the mirror module is 8192×1080pixels. From the experiments, the horizontal viewing window is almost two times wider than that without the mirror module. As a result, the hologram can be observed binocularly. © 2009 Society of Photo-Optical Instrumentation Engineers.Item Open Access Online distributed nonlinear regression via neural networks(IEEE, 2017) Ergen, Tolga; Kozat, Süleyman SerdarIn this paper, we study the nonlinear regression problem in a network of nodes and introduce long short term memory (LSTM) based algorithms. In order to learn the parameters of the LSTM architecture in an online manner, we put the LSTM equations into a nonlinear state space form and then introduce our distributed particle filtering (DPF) based training algorithm. Our training algorithm asymptotically achieves the optimal training performance. In our simulations, we illustrate the performance improvement achieved by the introduced algorithm with respect to the conventional methods.