Browsing Aysel Sabuncu Brain Research Center (BAM) by Title
Now showing items 118-137 of 183
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Neural ECM mimetics
(Elsevier, 2014)The consequence of numerous neurological disorders is the significant loss of neural cells, which further results in multilevel dysfunction or severe functional deficits. The extracellular matrix (ECM) is of tremendous ... -
Neurochemical differences between bipolar disorder type I and II in superior temporal cortices: a proton magnetic resonance spectroscopy study
(Elsevier B.V., 2018)Background: Despite the diagnostic challenges in categorizing bipolar disorder subtypes, bipolar I and II disorders (BD-I and BD-II respectively) are valid indices for researchers. Subtle neurobiological differences may ... -
A new class of cubic SPIONs as a dual-mode T1 and T2 contrast agent for MRI
(Elsevier, 2018)Superparamagnetic iron oxide nanoparticles (SPIONs) are widely used as a robust negative contrast agent on conventional MRI. In this study, we (a) synthesized a new class of cubic SPIONs as a dual-mode contrast agent in ... -
Novel object recognition is not affected by age despite age-related brain changes
(Scientific Research Publishing, 2013)Age-related memory impairments show a progressive decline across lifespan. Studies have demonstrated equivocal results in biological and behavioral outcomes of aging. Thus, in the present study we examined the novel object ... -
A novel, low-cost Anesthesia and injection system for Zebrafish Researchers
(Mary Ann Liebert, Inc. Publishers, 2018)In this study, we designed and developed a novel low-cost system for anesthetizing and injecting adult zebrafish. The system utilizes a gradual cooling method for the anesthesia and maintains the fish in a stable anesthetic ... -
Object-oriented segmentation of cell nuclei in fluorescence microscopy images
(Wiley-Liss, 2018)Cell nucleus segmentation remains an open and challenging problem especially to segment nuclei in cell clumps. Splitting a cell clump would be straightforward if the gradients of boundary pixels in-between the nuclei were ... -
Oligonucleotide delivery with cell surface binding and cell penetrating peptide amphiphile nanospheres
(American Chemical Society, 2015)A drug delivery system designed specifically for oligonucleotide therapeutics can ameliorate the problems associated with the in vivo delivery of these molecules. The internalization of free oligonudeotides is challenging, ... -
Optimizing electrode montages of transcranial direct current stimulation for attentional bias modification in early abstinent methamphetamine users
(Frontiers Media S.A., 2018)Introduction: Chronic use of most psychoactive drugs may lead to substance dependence and drug addiction. Drug addiction is a chronically relapsing disorder, and current pharmacological and behavioral therapies are not ... -
Osteoselection supported by phase separated polymer blend films
(Wiley, 2015)The instability of implants after placement inside the body is one of the main obstacles to clinically succeed in periodontal and orthopedic applications. Adherence of fibroblasts instead of osteoblasts to implant surfaces ... -
Peptide nanofiber scaffolds for multipotent stromal cell culturing
(Humana Press Inc., 2013)Self-assembled peptide nanofibers are versatile materials providing suitable platforms for regenerative medicine applications. This chapter describes the use of peptide nanofibers as extracellular matrix mimetic scaffolds ... -
Peptide-based materials for cartilage tissue regeneration
(Springer New York LLC, 2017)Cartilaginous tissue requires structural and metabolic support after traumatic or chronic injuries because of its limited capacity for regeneration. However, current techniques for cartilage regeneration are either invasive ... -
Perceived glossiness in high dynamic range scenes
(Association for Research in Vision and Ophthalmology, 2010)We investigated how spatial pattern, background, and dynamic range affect perceived gloss in brightly lit real scenes. Observers viewed spherical objects against uniform backgrounds. There were three possible objects. Two ... -
Perceptual asynchronies and the dual-channel differential latency hypothesis
(Cambridge University Press, 2010)The dual-channel differential latency hypothesis (Öğmen et al. 2004) successfully accounts for many aspects of the flash-lag effect (FLE). Here we use the dual-channel differential latency hypothesis to explain an illusion ... -
Perceptual averaging in individuals with autism spectrum disorder
(Frontiers Research Foundation, 2016)There is mounting evidence that observers rely on statistical summaries of visual information to maintain stable and coherent perception. Sensitivity to the mean (or other prototypical value) of a visual feature (e.g., ... -
Perceptual grouping-dependent lightness processing in human early visual cortex
(Association for Research in Vision and Ophthalmology, 2010)Lightness, the perceived relative achromatic reectance of a surface, depends strongly on the context within which the surface is viewed. Modest changes in the two-dimensional conguration or three-dimensional scene geometry ... -
Phase-correcting non-local means filtering for diffusion-weighted imaging of the spinal cord
(John Wiley & Sons, 2018)Purpose: DWI suffers from low SNR when compared to anatomical MRI. To maintain reasonable SNR at relatively high spatial resolution, multiple acquisitions must be averaged. However, subject motion or involuntary physiological ... -
Phase-sensitive reconstruction for fat-water separation in multi-coil acquisitions
(IEEE, 2016)Phase-sensitive steady-state free precession (PS-SSFP) is an effective technique for separating fat and water tissues, based on the phase difference between balanced steady-state free precession (bSSFP) bands. However, in ... -
Presentation of functional groups on self-assembled supramolecular peptide nanofibers mimicking glycosaminoglycans for directed mesenchymal stem cell differentiation
(Royal Society of Chemistry, 2017)Organizational complexity and functional diversity of the extracellular matrix regulate cellular behaviors. The extracellular matrix is composed of various proteins in the form of proteoglycans, glycoproteins, and nanofibers ... -
Profile-encoding reconstruction for multiple-acquisition balanced steady-state free precession imaging
(John Wiley and Sons Inc., 2017)Purpose: The scan-efficiency in multiple-acquisition balanced steady-state free precession imaging can be maintained by accelerating and reconstructing each phase-cycled acquisition individually, but this strategy ignores ...
