Browsing Aysel Sabuncu Brain Research Center (BAM) by Title
Now showing items 73-92 of 183
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Gene expression changes in aging zebrafish (Danio rerio) brains are sexually dimorphic
(BioMed Central, 2014)Background: Brain aging is a multi-factorial process due to both genetic and environmental factors. The zebrafish has recently become a popular model organism for examining aging and age-related diseases because as ... -
Generation of chimeric "aBS nanohemostat" complex and comparing its histomorphological in vivo effects to the traditional ankaferd hemostat in controlled experimental partial nephrectomy model
(Hindawi, 2013)Purpose. Using the classical Ankaferd Blood Stopper (ABS) solution to create active hemostasis during partial nephrectomy (PN) may not be so effective due to insufficient contact surface between the ABS hemostatic liquid ... -
Genetic logic gates enable patterning of amyloid nanofibers
(WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, 2019)Distinct spatial patterning of naturally produced materials is observed in many cellular structures and even among communities of microorganisms. Reoccurrence of spatially organized materials in all branches of life is ... -
Growth and differentiation of prechondrogenic cells on bioactive self-assembled peptide nanofibers
(American Chemical Society, 2013)Restoration of cartilage defect remains a challenge, as the current treatments are ineffective to return tissue to its health. Thus, developing therapies for treatment of cartilage tissue damage caused by common joint ... -
Growth factor binding on heparin mimetic peptide nanofibers
(American Chemical Society, 2012)Immobilization of growth factors in scaffolds is important for controlling their dose and bioactivity for regenerative medicine applications. Although numerous covalent and noncovalent immobilization strategies have been ... -
Growth hormone and insulin-like growth factor-I alter hippocampal excitatory synaptic transmission in young and old rats
(Age Company, 2013)In rats, as in humans, normal aging is characterized by a decline in hippocampal-dependent learning and memory, as well as in glutamatergic function. Both growth hormone (GH) and insulin-like growth factor-I (IGF-I) levels ... -
Growth hormone modulates hippocampal excitatory synaptic transmission and plasticity in old rats
(Elsevier, 2012)Alterations in the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor (AMPA-R) and N-methyl-D-aspartate receptor (NMDA-R) have been documented in aged animals and may contribute to changes in hippocampal-dependent ... -
Hadamard slice encoding for reduced-FOV diffusion-weighted imaging
(John Wiley & Sons, 2014)Methods: A 2D echo-planar RF pulse and matching multiband refocusing RF pulses were designed using the Shinnar-Le Roux algorithm to reduce band interference, and variable-rate selective excitation to shorten the pulse ... -
Hemifield asymmetry in the potency of exogenous auditory and visual cues
(Elsevier, 2011)Neurologically normal subjects misperceive the midpoints of lines (PSE) as reliably leftward of veridical center, a phenomenon known as pseudoneglect. This leftward bias reflects the dominance of the right cerebral hemisphere ... -
Heparin mimetic peptide nanofibers promote angiogenesis
(Biomacromolecules, 2011)New blood vessel formation (angiogenesis) is one of the most important processes required for functional tissue formation. Induction of angiogenesis is usually triggered by growth factors released by cells. Glycosaminoglycans ... -
Homozygosity mapping and targeted genomic sequencing reveal the game responsible for cerebellar hypoplasia and quadrupedal locomotion in a consanguineous kindred
(Cold Spring Harbor Laboratory Press, 2011)The biological basis for the development of the cerebro-cerebellar structures required for posture and gait in humans is poorly understood. We investigated a large consanguineous family from Turkey exhibiting an extremely ... -
Homozygous LAMC3 mutation links to structural and functional changes in visual attention networks
(Elsevier, 2018)The occipital lobe contains a substantial part of the neural machinery involved in visual perception. Mutations in the LAMC3 gene have recently been shown to cause complex bilateral occipital cortical gyration abnormalities. ... -
Huber function based reconstruction in accelerated phase-cycled bSSFP acquisitions for increased detection performance
(IEEE, 2017)Balanced steady-state free precession imaging suffers from irrecoverable signal losses, called banding artifacts. A common way to alleviate banding artifacts without sacrificing scan-efficiency is to use multiple-acquisition ... -
Human and machine learning in non- markovian decision making
(Public Library of Science, 2015)Humans can learn under a wide variety of feedback conditions. Reinforcement learning (RL), where a series of rewarded decisions must be made, is a particularly important type of learning. Computational and behavioral ... -
Imaging and surgical outcomes of spinal tumors in 18 dogs and one cat
(The Korean Society of Veterinary Science., 2016)Clinical and magnetic resonance imaging (MRI) findings, histological appearances and surgical outcomes of 18 dogs and one cat with spinal tumors are presented. Medical records of the cases admitted for spinal disorders ... -
Improving pancreatic islet in vitro functionality and transplantation efficiency by using heparin mimetic peptide nanofiber gels
(Elsevier, 2015)Pancreatic islet transplantation is a promising treatment for type 1 diabetes. However, viability and functionality of the islets after transplantation are limited due to loss of integrity and destruction of blood vessel ... -
Incorporating family function into chronic pain disability: the role of catastrophizing
(Hindawi Publishing Corporation, 2016)Background: Observers' responses to pain are recently investigated to more comprehensively explain chronic pain (CP) and disability. However, the role of family context, defined as interference in roles, communication, and ... -
Integrated assessment of visual perception abnormalities in psychotic disorders and relationship with clinical characteristics
(Cambridge University Press, 2019)Background-The visual system is recognized as an important site of pathology and dysfunction in schizophrenia. In this study, we evaluated different visual perceptual functions in patients with psychotic disorders using a ... -
Interpretability analysis for Turkish word embeddings
(IEEE, 2018)Kelime temsilleri, doğal dil işleme (DDİ) uygulamalarında sağladıkları önemli performans artışları dolayısıyla günümüzde yaygın olarak çalışılmakta ve kullanılmaktadır. Kelime temsili öğrenen algoritmalar, etiketsiz büyük ... -
Intracellular accumulation of gold nanoparticles leads to inhibition of macropinocytosis to reduce the endoplasmic reticulum stress
(Nature Publishing Group, 2017)Understanding the toxicity of nanomaterials remains largely limited to acute cellular response, i.e., short-Term in vitro cell-death based assays, and analyses of tissue-and organ-level accumulation and clearance patterns ...
