A novel ODN delivery platform: CpG-ODN-loaded exosome nanovesicles

Date
2012-05
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Abstract Book 2012, 10th CIMT Annual Meeting
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Association for Cancer Immunotherapy
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135 - 136
Language
English
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Abstract

Exosomes are naturally occurring, membranous nanovesicles of 40-100 nm in diameter. They arise from the endocytic cellular pathway through three stages: (i) formation of endocytic vesicles ii) multivesicular bodies (MVBs) formation in the cytosol and (iii) fusion of the MVBs with the plasma membrane to release their nanovesicular cargoes (1, 2).

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Published Version (Please cite this version)