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      Advances in nanoparticle‐based medical diagnostic and therapeutic techniques

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      Author(s)
      Sardan, Melis
      Özkan, Alper Devrim
      Zengin, Aygül
      Tekinay, Ayşe B.
      Güler, Mustafa O.
      Editor
      Güler, Mustafa O.
      Tekinay, Ayşe B.
      Date
      2016-03-11
      Publisher
      John Wiley & Sons
      Pages
      197 - 234
      Language
      English
      Type
      Book Chapter
      Item Usage Stats
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      331
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      Book Title
      Therapeutic nanomaterials
      Abstract
      Advances in modern medicine have eliminated several major causes of human mortality and considerably extended life expectancies around the world; however, this increase in the global age average has also boosted the incidences of age‐associated disorders. These conditions, such as cancer, neurodegenerative disorders, and cardiovascular disease, severely decrease the quality of life for the affected but are highly polymorphic and often difficult to treat. This chapter describes the characteristics of nanoparticle (NP) contrast agents (CAs) proposed for use in medical imaging, and details the surface modification methods used to designate specific targets for their attachment. It then compares their effectiveness and toxicity compared to conventional methods of contrast enhancement, and discusses the contribution that nanoscience has had, and will have, on medical imaging and disease diagnosis at large.
      Keywords
      Computed tomography
      Contrast enhancement
      Disease diagnosis
      Fluorescence imaging
      Medical diagnostics tools
      Medical imaging
      Nanoparticle
      Surface modification methods
      Permalink
      http://hdl.handle.net/11693/50913
      Published Version (Please cite this version)
      https://doi.org/10.1002/9781118987483.ch9
      https://doi.org/10.1002/9781118987483
      Collections
      • Institute of Materials Science and Nanotechnology (UNAM) 2098
      • Nanotechnology Research Center (NANOTAM) 1125
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