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dc.contributor.authorDemirel, O. B.en_US
dc.contributor.authorSaritas, E. U.en_US
dc.date.accessioned2019-02-12T06:48:54Z
dc.date.available2019-02-12T06:48:54Z
dc.date.issued2017en_US
dc.identifier.issn2365-9033
dc.identifier.urihttp://hdl.handle.net/11693/49285
dc.description.abstractMagnetic Particle Imaging (MPI) relies on time-varying magnetic fields to generate an image of the spatial distribution of superparamagnetic iron oxide nanoparticles. However, these oscillating magnetic fields form electric field patterns within the body, which in turn can cause peripheral nerve stimulations (PNS), also known as magnetostimulation. To prevent potential safety hazards and to optimize the scanning parameters such as field-of-view (FOV) and scanning speed in MPI, the factors that affect drive field magnetostimulation limits need to be determined accurately. In this work, we investigate the effects of the duty cycle on magnetostimulation thresholds in MPI. We performed human subject experiments by using a highly homogenous solenoidal coil on the upper arm of six subjects. Six different duty cycles ranging between 5 % and 100 % were applied at 25 kHz. Accordingly, magnetostimulation limits first decrease and then increase with increasing duty cycle, reaching a maximum at 100 % duty cycle. Since high duty cycles would be the preferred operating mode for rapid imaging with MPI, these results have promising implications for future human-sized MPI systems.en_US
dc.language.isoEnglishen_US
dc.source.titleInternational Journal on Magnetic Particle Imagingen_US
dc.relation.isversionofhttps://doi.org/10.18416/ijmpi.2017.1703010en_US
dc.subjectMagnetostimulation thresholden_US
dc.subjectPeripheral nerve stimulationen_US
dc.subjectDuty cycleen_US
dc.subjectMagnetic particle imagingen_US
dc.titleEffects of duty cycle on magnetostimulation thresholds in MPIen_US
dc.typeArticleen_US
dc.departmentDepartment of Electrical and Electronics Engineeringen_US
dc.departmentNational Magnetic Resonance Research Center UMRAMen_US
dc.departmentInterdisciplinary Program in Neuroscienceen_US
dc.citation.spage1en_US
dc.citation.epage7en_US
dc.citation.volumeNumber3en_US
dc.citation.issueNumber1en_US
dc.identifier.doi10.18416/ijmpi.2017.1703010en_US
dc.publisherInfinite Science Publishingen_US


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