Interdisciplinary Program in Neuroscience

Zebrafish aging models and possible interventions

Birand, Dilan Ç.; Erbaba, Begün; Özdemir, Ahmet T.; Kafalıgönül, Hulusi; Adams, Michelle (InTechOpen Press, 2018)

Across the world, the aging population is expanding due to an increasing average life expectancy. The percentage of elderly over the age of 65 is expected to be more than 15% of the total world population by 2025. As the ...

Examining the effects of audiovisual associations on motion perception through task-based fMRI

Kafaligonul, H. (Yerkure Tanitim ve Yayincilik Hizmetleri A.S., 2018)

Examining the effects of audiovisual associations on motion perception through task-based fMRI Objective: Previous studies showed that associative learning can lead to drastic changes in perceptual experience and unexpected ...

Abnormal subcortical activity in congenital mirror movement disorder with RAD51 mutation

Demirayak, P.; Onat, O. E.; Gevrekci, A. Ö.; Gülsüner, S.; Uysal, H.; Bilgen, R.; Doerschner, K.; Özçelik, T.; Boyacı, H. (Turkish Society of Radiology, 2018)

PURPOSE Congenital mirror movement disorder (CMMD) is characterized by unintended, nonsuppressible, homologous mirroring activity contralateral to the movement on the intended side of the body. In healthy controls, unilateral ...

Set similarity modulates object tracking in dynamic environments

Akyuz, S.; Munneke, J.; Corbett, J. E. (Springer New York LLC, 2018)

Based on the observation that sports teams rely on colored jerseys to define group membership, we examined how grouping by similarity affected observers’ abilities to track a “ball” target passed between 20 colored circle ...

Attentional bias to threat-related information among individuals with dental complaints: The role of pain expectancy

Dehghani, M.; Mohammadi, S.; Sharpe, L.; Khatibi, A. (Frontiers Media S.A., 2018)

Expecting pain can be perceived as a threat may involve recruitment of cognitive strategies (such as attentional avoidance) which might help the person to reduce distress. The ecological validity of the paradigms aiming ...

Optimizing electrode montages of transcranial direct current stimulation for attentional bias modification in early abstinent methamphetamine users

Shahbabaie, A.; Hatami, J.; Farhoudian, A.; Ekhtiari, H.; Khatibi, A.; Nitsche, M. A. (Frontiers Media S.A., 2018)

Introduction: Chronic use of most psychoactive drugs may lead to substance dependence and drug addiction. Drug addiction is a chronically relapsing disorder, and current pharmacological and behavioral therapies are not ...

Zebrafish-A model organism for studying the neurobiological mechanisms underlying cognitive brain aging and use of potential interventions

Adams, M. M.; Kafaligonul, H. (Frontiers Media S.A., 2018)

Classically, the zebrafish model organism has been used to elucidate the genetic and cellular mechanisms related to development since the embryo forms and grows externally following fertilization. This provides insight ...

Cholinergic receptor nicotinic alpha 5 (CHRNA5) RNAi is associated with cell cycle inhibition, apoptosis, DNA damage response and drug sensitivity in Breast cancer

Koker, S. C.; Jahja, E.; Shehwana, H.; Keskus, A. G.; Konu, O. (Public Library of Science, 2018)

Cholinergic Receptor Nicotinic Alpha 5 (CHRNA5) is an important susceptibility locus for nicotine addiction and lung cancer. Depletion of CHRNA5 has been associated with reduced cell viability, increased apoptosis and ...

Test-retest reliability of myelin imaging in the human spinal cord: Measurement errors versus region-and aging-induced variations

Lévy, S.; Guertin, M. -C.; Khatibi, A.; Mezer, A.; Martinu, K.; Chen, J. -I.; Stikov, N.; Rainville, P.; Cohen-Adad, J. (Public Library of Science, 2018)

Purpose To implement a statistical framework for assessing the precision of several quantitative MRI metrics sensitive to myelin in the human spinal cord: T1, Magnetization Transfer Ratio (MTR), saturation imposed by an ...

Temporal ventriloquism along the path of apparent motion: speed perception under different spatial grouping principles

Ogulmus, C.; Karacaoglu, M.; Kafaligonul, H. (Springer Verlag, 2018)

The coordination of intramodal perceptual grouping and crossmodal interactions plays a critical role in constructing coherent multisensory percepts. However, the basic principles underlying such coordinating mechanisms ...

Semantic structure and interpretability of word embeddings

Senel, L. K.; Utlu, I.; Yucesoy, V.; Koc, A.; Cukur, T. (Institute of Electrical and Electronics Engineers, 2018)

Dense word embeddings, which encode meanings of words to low-dimensional vector spaces, have become very popular in natural language processing (NLP) research due to their state-of-the-art performances in many NLP tasks. ...

BSSFP görüntülemede eliptik sinyal modeline dayali eşzamanlı parametre tahmini

Keskin, K.; Cukur, T. (Institute of Electrical and Electronics Engineers, 2018)

Faz döngülü dengeli kararlı-durum serbest devinim (bSSFP) görüntüleme tekniginde, görüntüde oluşan rezonans dışı frekanslardan kaynaklı sinyal düşüşlerinin uzamsal konumunu kaydırmak amacıyla her çekimde RF darbelerinin ...

Real-time three-dimensional image reconstruction using alternating direction method of multipliers for magnetic particle imaging

İlbey, S.; Güngör, A.; Top, C. B.; Sarıtaş, E. Ü.; Güven, H. E. (Institute of Electrical and Electronics Engineers, 2018)

Manyetik Parçacık Görüntüleme (MPG), süperparamanyetik demiroksit nanoparçacıklarının uzamsal dağılımını tespit etmekte kullanılan görece yeni bir medikal görüntüleme yöntemidir. MPG’de görüntü geriçatımı için kullanılan ...