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Aflatoxin genotoxicity is associated with a defective DNA damage response bypassing p53 activation
(John Wiley & Sons, 2011)
Background: Hepatocellular carcinoma (HCC) is a leading cause of cancer deaths. Aflatoxins, which may play a causative role in 5-28% of HCCs worldwide, are activated in liver cells and induce principally G→T mutations, ...