Using nanogap in label - free impedance based electrical biosensors to overcome electrical double layer effect
Okyay, A. K.
Guler, M. O.
889 - 897
MetadataShow full item record
Please cite this item using this persistent URLhttp://hdl.handle.net/11693/36368
Point-of-care biosensor applications require low-cost and low-power solutions. They offer being easily accessible at home site. They are usable without any complex sample handling or any kind of special expertise. Impedance spectroscopy has been utilized for point-of-care biosensor applications; however, electrical double layer formed due to ions in the solution of interest has been a challenge, due to shielding of the electric field used for sensing the target molecules. Here in this study, we demonstrate a nanogap based biosensor structure with a relatively low frequency (1–100 kHz) measurement technique, which not only eliminates the undesired shielding effect of electrical double layer but also helps in minimizing the measurement volume and enabling low concentration (µ molar level) detection of target molecules (streptavidin). Repeatability and sensitivity tests proved stable and reliable operation of the sensors. These biosensors might offer attributes such as low-cost label-free detection, fast measurement and monolithic chip integrability.
Showing items related by title, author, creator and subject.
Experimental results for 2D magnetic resonance electrical impedance tomography (MR-EIT) using magnetic flux density in one direction Birgül, Ö.; Eyüboğlu, B. M.; İder, Y. Z. (Institute of Physics Publishing, 2003)Magnetic resonance electrical impedance tomography (MR-EIT) is an emerging imaging technique that reconstructs conductivity images using magnetic flux density measurements acquired employing MRI together with conventional ...
Hafalir, F. S.; Oran, O. F.; Gurler, N.; Ider, Y. Z. (Institute of Electrical and Electronics Engineers Inc., 2014)Images of electrical conductivity and permittivity of tissues may be used for diagnostic purposes as well as for estimating local specific absorption rate distributions. Magnetic resonance electrical properties tomography ...
Tanrisever, F.; Derinkuyu, K.; Jongen, G. (Elsevier Ltd, 2015)Abstract In this paper, we examine the organization and the functioning of the Dutch electricity market. First we describe the organization of the Dutch electricity supply chain and the role of the main market participants ...