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dc.contributor.advisorÇukur, Emine Ülkü Sarıtaşen_US
dc.contributor.authorDemirel, Ömer Buraken_US
dc.date.accessioned2017-07-21T08:33:42Z
dc.date.available2017-07-21T08:33:42Z
dc.date.copyright2017-07
dc.date.issued2017-07
dc.date.submitted2017-07-19
dc.identifier.urihttp://hdl.handle.net/11693/33490
dc.descriptionCataloged from PDF version of article.en_US
dc.descriptionThesis (M.S.): Bilkent University, Department of Electrical and Electronics Engineering, İhsan Doğramacı Bilkent University, 2017.en_US
dc.descriptionIncludes bibliographical references (leaves 54-58).en_US
dc.description.abstractMagnetic Particle Imaging (MPI) is a new imaging modality that utilizes nonlinear magnetization of superparamagnetic tracers, with high sensitivity and zeroionizing radiation advantages. Since the introduction of MPI in 2005, there have been substantial contributions to pre-clinical applications such as cancer imaging, cell tracking, and angiography. These studies have promising implications for future clinical human-sized MPI systems. However, the time-varying magnetic fields that are used during image acquisition are subject to human safety concerns, especially in applications that require rapid imaging. By forming electric field patterns in the body, these fields may result in peripheral nerve stimulation, also known as magnetostimulation. To prevent potential stimulations; the effects of frequency, duration, and direction of the fields, as well as body part size were previously investigated. This thesis investigates the effects of duty cycle and fat/water tissue ratio on magnetostimulation thresholds for the drive field in MPI. Human subject experiments with in-house magnetostimulation setup were conducted at 25 kHz, followed by anatomical Magnetic Resonance Imaging (MRI) of the subjects. Accordingly, magnetostimulation thresholds first decrease then increase with increasing duty cycle and reach a maximum at 100% duty cycle. The results also show that the thresholds are strongly correlated with fat/water tissue ratio. Finally, this thesis also demonstrates that MPI image quality can be preserved for rapid scanning scenarios within the human safety limits.en_US
dc.description.statementofresponsibilityby Ömer Burak Demirel.en_US
dc.format.extentxiv, 69 leaves : illustrations (some color), charts ; 29 cmen_US
dc.language.isoEnglishen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMagnetic particle imagingen_US
dc.subjectMagnetostimulation thresholden_US
dc.subjectPeripheral nerve stimulationen_US
dc.subjectRapid imagingen_US
dc.titleSafety limits & rapid scanning methods in magnetic particle imagingen_US
dc.title.alternativeManyetik parçacık görüntüleme'de güvenlik sınırlamaları & hızlı tarama yöntemlerien_US
dc.typeThesisen_US
dc.departmentDepartment of Electrical and Electronics Engineeringen_US
dc.publisherBilkent Universityen_US
dc.description.degreeM.S.en_US
dc.identifier.itemidB156003
dc.embargo.release2018-07-18


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