Browsing Graduate Program in Neuroscience - Ph.D. / Sc.D. by Title
Now showing items 1-14 of 14
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Age-dependent effects of short-term intermittent fasting and rapamycin treatment in Zebrafish (Danio Rerio) brain
(Bilkent University, 2020-05)World populations are rapidly aging, and there is an urgent need to develop interventions that prevent or reverse age-related deterioration of health. To date, several approaches have been developed to extend health span. ... -
Behavioral and computational investigation of the effect of prior knowledge on visual perception
(Bilkent University, 2021-01)Visual perception results from the dynamic interaction of bottom-up and topdown processes. Top-down prior knowledge and expectations can guide us to predict upcoming events and even determine what we see in an ambiguous ... -
Cortical processes underlying attentional modulations of dynamic vision
(Bilkent University, 2022-09)Visual attention is one of the most fundamental cognitive functions guiding and influencing a various number of processes. However, how different neural mechanisms are modulated by selective attention to process information ... -
The effect of context-dependent lightness on contrast detection and identification, and its neural correlates
(Bilkent University, 2017-10)Perceived contrast of a grating varies with its background (or mean) luminance: of the two gratings with the same photometric contrast the one on higher luminance background appears to have higher contrast. On the other ... -
Effects of aging, diet and potential genetic interventions on the levels of Smurf2 and its interacting partners in Zebrafish (Danio Rerio) brain
(Bilkent University, 2020-09)Aging is a natural process that is ultimate combination of numerous intrinsic and extrinsic changes in an organism. Contrary the common belief, brain aging is not a loss of neurons while it has been shown that subtle ... -
Genetic and environmental interventions altering the course of brain aging: evidence from the zebrafish (Danio Rerio) model
(Bilkent University, 2021-04)Age-related cognitive decline occurs during normal aging, although there is no prominent neural loss in the brain. Subtle molecular alterations in synaptic and cellular dynamics are likely underlying these cognitive ... -
Genetic influences on cortical structure and function
(Bilkent University, 2018-07)Structure and function of the human central nervous system is determined by both genetic and environmental in uences. One of the fundamental quests in neuroscience studies is to determine to what degree each of these ... -
Identification of modulatory functions of TP53, estrogen signaling, and 14q32.31 miRNA cluster on CHRNA5 knock-down expression profile and development of syneRgy APP
(Bilkent University, 2021-09)Cholinergic receptor subunit alpha 5 (CHRNA5) is a ligand-gated ion channel expressed in not only the nervous system but also other tissues. Differential expression and the polymorphisms of CHRNA5 have been associated with ... -
Identification of preclinical implications for novel indole-benzimidazoles and phenothiazines using in vitro cancer cell line and in vivo zebrafish models
(Bilkent University, 2020-09)Breast cancer (BC) and hepatocellular carcinoma (HCC) are two major health problems with significant mortality rates. Although drug therapies are available, therapeutic success remains limited. Because of low bioavailability, ... -
Investigating motion detection of aging zebrafish with optomotor response
(Bilkent University, 2021-07)Various aspects of visual functioning including motion perception have been shown to be significantly altered throughout aging. Contrary to the traditional view focusing on structural changes in the eye and retina, ... -
Natural speech representations in the human brain during a cocktail party
(Bilkent University, 2021-08)Humans are remarkably adept in selectively listening to a desired speaker in a crowded environment, while filtering out non-target speakers in the background. Attention is key to solving this difficult cocktail-party task, ... -
Probing sensory plasticity with rapid forms of motion adaptation
(Bilkent University, 2020-09)Perception is shaped by both immediate pattern of sensory inputs and previous experience with the external environment. Visual adaptation, a temporary change in perception following exposure to a stimulus, has been widely ... -
Spatially informed voxelwise modeling and dynamic scene category representation in the human brain
(Bilkent University, 2021-12)Humans have an impressive ability to rapidly process global information in natural scenes to infer their category. Yet, it remains unclear whether and how scene categories observed dynamically in the natural world are ... -
Transcriptomic alterations in the aged brain with and without dietary and dietary- mimetic manipulations
(Bilkent University, 2021-12)Aside from many genetic and environmental influences on the brain, aging itself is a significant risk factor for accelerated cognitive decline, making aging research crucial due to the increasing population age in our era. ...
