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      • Theses - Department of Molecular Biology and Genetics
      • Dept. of Molecular Biology and Genetics - Master's degree
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      Functional analysis of transgelin in breast cancer 

      Değer, Nazlı (Bilkent University, 2018-06)
      Transgelin (TAGLN) is an actin-binding protein. It is highly expressed in fibroblasts and smooth muscle cells. In smooth muscle cells, it takes part in processes including motility and differentiation and also it has a ...
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      Investigating the role of the mediator complex in estrogen receptor alpha-mediated transcription 

      Canavar, Tuğçe (Bilkent University, 2018-07)
      Mediator is the most important coregulator in eukaryotic transcription. It conveys the signals received from transcriptional activators on enhancer sequences to transcription machinery on promoter regions. Although Mediator ...
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      Immunomodulatory effects of exosomes: promising candidates in immunotherapy 

      Kılgöz, Havva Özgen (Bilkent University, 2018-08)
      Exosomes are type of extracellular vesicles secreted from almost all cell types and carry numerous biological molecules such as nucleic acids, protein and lipids. They mediate many cellular processes including cellular ...
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      Evaluation of TAGLN as a diagnostic marker in breast cancer 

      Köseer, Ayşe Sedef (Bilkent University, 2018-08)
      Silecing of tumor suppressor genes via CpG hypermethylation in promoter regions is one of the frequent events occurring in different types of cancers. These genes have the potential as a diagnostic or a prognostic ...
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      Identification of the roles played by IKKε in hepatocellular and colorectal carcinogenesis 

      Kahya, Uğur (Bilkent University, 2018-07)
      Hepatocellular carcinomas (HCC) and colorectal carcinomas (CRC) are among the most common cancers worldwide with high mortality rates. While HCC affecting mostly underdeveloped countries, CRC is a disease that mainly occur ...
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      Identification of long non-coding RNAs overcoming tamoxifen resistance in estrogen receptor alpha positive breast cancer 

      Bal, Hilal (Bilkent University, 2017-09)
      Most of the breast cancer incidences all over the world fall into Estrogen Receptor alpha (ERα)-positive breast cancer subtype, which are treated with endocrine therapy. Tamoxifen, a selective ER modulator drug, is the ...
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      Investigation of the role of cGAMP in differentiation of T lymphocytes 

      Yıldız, Begüm (Bilkent University, 2016-10)
      STING is the pivotal mediator for the recognition of host and pathogenic cytosolic dsDNA as well as cyclic di-nucleotides metabolites from microbes. STING can either recognize DNA itself or sense the presence of cGAMP, ...
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      Regulation of mineralocorticoid receptor and its downstream targets by estrogen and aldosterone in breast cancer 

      Çoban, Bircan (Bilkent University, 2016-11)
      Many women suffer from breast cancer worldwide thus accurate diagnosis of this disease has become an important issue for treatment options and improved clinical outcomes. Members of steroid hormone receptors, are a subfamily ...
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      Elucidation of Sorafenib resistance mechanisms in hepatocellular carcinoma 

      Boyacıoğlu, Zeynep (Bilkent University, 2018-07)
      Hepatocellular Carcinoma (HCC) is the sixth most common type of cancer and the second leading cause of cancer-related deaths worldwide. Currently, Sorafenib is the only approved first-line treatment option for unresectable ...
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      Identification of general transcription Factor-Two-E and mediator complex interactions in the context of pre-initiation complex formation 

      Karasu, Onur Rojhat (Bilkent University, 2018-06)
      Transcription is a multistep process which requires the presence of many different proteins and protein complexes. The minimal protein components enabling transcription to happen are identified to execute the event in ...
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      AuthorAbdüsselamoğlu, Merve Deniz (1)Akbar, Muhammad Waqas (1)Akdemir, İmran (1)Akçay, Abbas Güven (1)Assidicky, Ridho (1)Ayyıldız, Zeynep Özge (1)Açıkgöz, Azer Aylin (1)Bal, Hilal (1)Barış, Yasemin (1)Bayın, N. Sumru (1)... View MoreKeywordsBreast cancer (8)Breast Cancer (4)CHRNA5 (4)Transcription (4)Biomarker (3)Diagnosis (3)HCC (3)Mediator Complex (3)Pre-initiation Complex (3)UPR (3)... View MoreDate Issued2016 (9)2013 (8)2014 (8)2018 (8)2019 (7)2010 (6)2017 (6)2011 (3)2015 (2)2012 (1)Type
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