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Transcript variants of CELF2 gene as unique prognostic indicators in breast cancer
(Bilkent University, 2022-08)
Breast cancer (BC) is the most common malignant tumor in women around the world. Aside from finding a cure for this disease, it is also critical to identify prognostic biomarkers that can help clinicians intervene with the ...
Development and validation of methods for the diagnosis of lung cancer via serological biomarkers
(Bilkent University, 2019-02)
Over 10% of all new cancer cases are lung cancer. Moreover, estimates till 2030 indicate that already increasing lung cancer incidences will keep increasing, especially in developing countries like Turkey. Lung cancer, the ...
In silico validation of prognostic mRNA signature in gastric cancer and identification and validation of novel gastric tissue specific reference genes for quantitative PCR
(Bilkent University, 2021-07)
Gastric adenocarcinoma is a molecularly and histologically heterogeneous neoplasm with a predictively disastrous outcome if undiagnosed at early stages. Amidst global declines of gastric cancer rates, it remains the 5th ...
Development of methods for identification and characterization of autologous antibody responses in Small Cell Lung Cancer and Behcet’s Disease
(Bilkent University, 2016-08)
Autologous antibodies are known to be elicited in Behçet’s Disease (BD) and Small Cell Lung Cancer (SCLC). SCLC consists 15-20% of all lung cancer cases. It is follows a most aggressive course and generally patients are ...
Evaluation of TAGLN as a diagnostic marker in breast cancer
(Bilkent University, 2018-08)
Silecing of tumor suppressor genes via CpG hypermethylation in promoter regions
is one of the frequent events occurring in different types of cancers. These genes
have the potential as a diagnostic or a prognostic ...